Forskning ved Københavns Universitet - Københavns Universitet

Leise Riber
Leise Riber


Aktuel forskning

Interactions of bacterial communities and prevalence of antimicrobial resistance genes in natural environments. Molecular mechanisms involved in spread and acquisition of antibiotics resistance through horizontal gene transfer among bacterial populations. Dynamics of plasmid transfer and stability within bacterial species in complex environments. Transfer frequencies and host range of various conjugative plasmids are studied by a cultivation independent single cell based transfer-reporter gene approach using the Green Fluorescent Protein (GFP) together with Fluorescence-activated cell sorting (FACS).

Molecular microbiology; Construction and optimization of molecular methods for tagging plasmids and bacterial chromosomes for use in the transfer-reporter gene based system when studying horizontal gene transfer on a single cell level.

Plasmid biology; Studying and characterizing environmental conjugative plasmids with respect to finding gene determinants involved in plasmid dependent regulation of biofilm formation and plasmid transfer.

Udvalgte publikationer

  1. Hda-mediated inactivation of the DnaA protein and dnaA gene autoregulation act in concert to ensure homeostatic maintenance of the Escherichia coli chromosome

    Riber, Leise, Olsson, J. A., Jensen, R. B., Skovgaard, O., Dasgupta, S., Marinus, M. G. & Løbner-Olesen, A., 1 aug. 2006, I : Genes & Development. 20, 15, s. 2121-34 14 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  2. Coordinated replication and sequestration of oriC and dnaA are required for maintaining controlled once-per-cell-cycle initiation in Escherichia coli

    Riber, Leise & Løbner-Olesen, A., 1 aug. 2005, I : Journal of Bacteriology. 187, 16, s. 5605-13 9 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  3. Suppressors of DnaAATP imposed overinitiation in Escherichia coli

    Charbon, G., Riber, Leise, Cohen, M., Skovgaard, O., Fujimitsu, K., Katayama, T. & Løbner-Olesen, Anders, 2011, I : Molecular Microbiology. 79, 4, s. 914-928 15 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  4. Udgivet
  5. Loss of Hda activity stimulates replication initiation from I-box, but not R4 mutant origins in Escherichia coli

    Riber, Leise, Fujimitsu, K., Katayama, T. & Løbner-Olesen, A., 1 jan. 2009, I : Molecular Microbiology. 71, 1, s. 107-22 16 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

ID: 17515397