Forskning ved Københavns Universitet - Københavns Universitet

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Søren Brøgger Christensen
Søren Brøgger Christensen

Professor emeritus

Author or coauthor more than 185 articles or bookchapters in scientific journals or books, coeditor on 2 books and coinventor on 8 patents, h-index 50.

The main topic of research has been isolation of natural products with biological activities and optimizing of their structures to develop new drugs. The focus points have been development of mipsagargin from thapsigargin for treatment of cancer diseases and development of malaria drugs from licochalcone A.

Udvalgte publikationer

  1. Udgivet

    Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells

    Griend, D. J. V., Antony, L., Dalrymple, S. L., Xu, Y., Christensen, Søren Brøgger, Denmeade, S. R. & Isaacs, J. T., 2009, I : Molecular Cancer Therapeutics. 8, 5, s. 1340-1349

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  2. Udgivet

    Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase

    Paulsen, E. S., Villadsen, J., Tenori, E., Liu, H., Bonde, D. F., Lie, M. A., Bublitz, M., Olesen, C. L., Autzen, Henriette Elisabeth, Dach, I., Sehgal, P., Nissen, P., Møller, J., Schiøtt, B. & Christensen, Søren Brøgger, 9 maj 2013, I : Journal of Medicinal Chemistry. 56, 9, s. 3609-19 11 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

ID: 1300951