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4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Jean-Marie Receveur
  • Emelie Bjurling
  • Ulven, Trond
  • Paul Brian Little
  • Pia K Nørregaard
  • Thomas Högberg
Synthesis, in vitro biological evaluation and structure-activity relationships of 4-acylamino-and 4-ureidobenzamides as novel hMCH1R-antagonists are disclosed. The nature of the amine side chains could be varied considerably in contrast to the central benzamide scaffold and aromatic substituents.
OriginalsprogEngelsk
TidsskriftBioorganic & Medicinal Chemistry Letters
Vol/bind14
Udgave nummer20
Sider (fra-til)5075-5080
Antal sider6
ISSN0960-894X
DOI
StatusUdgivet - 18 okt. 2004

ID: 189159527