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A 9-week randomized trial comparing a chronotherapeutic intervention (wake and light therapy) to exercise in major depressive disorder patients treated with duloxetine

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Martiny, Klaus
  • Else Refsgaard
  • Vibeke Lund
  • Marianne Lunde
  • Lene Sørensen
  • Britta Thougaard
  • Lone Lindberg
  • Per Bech
The onset of action of antidepressants often takes 4 to 6 weeks. The antidepressant effect of wake therapy (sleep deprivation) comes within hours but carries a risk of relapse. The objective of this study was to investigate whether a new chronotherapeutic intervention combining wake therapy with bright light therapy and sleep time stabilization could induce a rapid and sustained augmentation of response and remission in major depressive disorder.
OriginalsprogEngelsk
TidsskriftPrimary Care Companion to C N S Disorders
Vol/bind73
Udgave nummer9
Sider (fra-til)1234-42
Antal sider9
ISSN2155-7772
DOI
StatusUdgivet - 2012

ID: 48422222