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A botanical compound, Padma 28, increases walking distance in stable intermittent claudication

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A botanical compound, Padma 28, increases walking distance in stable intermittent claudication. / Drabaek, H; Mehlsen, J; Himmelstrup, H; Winther, K.

I: Angiology, Bind 44, Nr. 11, 01.11.1993, s. 863-7.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Drabaek, H, Mehlsen, J, Himmelstrup, H & Winther, K 1993, 'A botanical compound, Padma 28, increases walking distance in stable intermittent claudication', Angiology, bind 44, nr. 11, s. 863-7.

APA

Drabaek, H., Mehlsen, J., Himmelstrup, H., & Winther, K. (1993). A botanical compound, Padma 28, increases walking distance in stable intermittent claudication. Angiology, 44(11), 863-7.

Vancouver

Drabaek H, Mehlsen J, Himmelstrup H, Winther K. A botanical compound, Padma 28, increases walking distance in stable intermittent claudication. Angiology. 1993 nov 1;44(11):863-7.

Author

Drabaek, H ; Mehlsen, J ; Himmelstrup, H ; Winther, K. / A botanical compound, Padma 28, increases walking distance in stable intermittent claudication. I: Angiology. 1993 ; Bind 44, Nr. 11. s. 863-7.

Bibtex

@article{5dcbbc01abf24821a842c05b5f184abf,
title = "A botanical compound, Padma 28, increases walking distance in stable intermittent claudication",
abstract = "Thirty-six patients with a median age of sixty-seven years and a median duration of intermittent claudication of five years were randomized to either active treatment with Padma 28 or placebo. The effect of treatment was quantified by measurements of systemic and peripheral systolic blood pressures and by measurements of the pain-free and the maximal walking distance on a treadmill. The ankle pressure index (ankle systolic pressure/arm systolic pressure) was calculated. The group randomized to active treatment received two tablets bid containing 340 mg of a dried herbal mixture composed according to an ancient lamaistic preparation (Padma 28). After active treatments, administered over a period of four months in a double-blinded, randomized design, the patients allocated to this group attained a significant increase in the pain-free walking distance from 52 m (20-106) to 86 m (24-164; P <0.05) and in the maximal walking distance from 115 m (72-218) to 227 m (73- > 1,000; P <0.05). The patient-group receiving placebo treatments did not show any significant changes in either the painfree or the maximal walking distance. The authors could not demonstrate any significant changes in the ankle pressure index either during active or during placebo treatment. In conclusion, this study has shown that treatment with Padma 28 over a period of four months significantly increased the walking distance in patients with stable, intermittent claudication of long duration.",
author = "H Drabaek and J Mehlsen and H Himmelstrup and K Winther",
year = "1993",
month = nov,
day = "1",
language = "English",
volume = "44",
pages = "863--7",
journal = "Angiology",
issn = "0003-3197",
publisher = "SAGE Publications",
number = "11",

}

RIS

TY - JOUR

T1 - A botanical compound, Padma 28, increases walking distance in stable intermittent claudication

AU - Drabaek, H

AU - Mehlsen, J

AU - Himmelstrup, H

AU - Winther, K

PY - 1993/11/1

Y1 - 1993/11/1

N2 - Thirty-six patients with a median age of sixty-seven years and a median duration of intermittent claudication of five years were randomized to either active treatment with Padma 28 or placebo. The effect of treatment was quantified by measurements of systemic and peripheral systolic blood pressures and by measurements of the pain-free and the maximal walking distance on a treadmill. The ankle pressure index (ankle systolic pressure/arm systolic pressure) was calculated. The group randomized to active treatment received two tablets bid containing 340 mg of a dried herbal mixture composed according to an ancient lamaistic preparation (Padma 28). After active treatments, administered over a period of four months in a double-blinded, randomized design, the patients allocated to this group attained a significant increase in the pain-free walking distance from 52 m (20-106) to 86 m (24-164; P <0.05) and in the maximal walking distance from 115 m (72-218) to 227 m (73- > 1,000; P <0.05). The patient-group receiving placebo treatments did not show any significant changes in either the painfree or the maximal walking distance. The authors could not demonstrate any significant changes in the ankle pressure index either during active or during placebo treatment. In conclusion, this study has shown that treatment with Padma 28 over a period of four months significantly increased the walking distance in patients with stable, intermittent claudication of long duration.

AB - Thirty-six patients with a median age of sixty-seven years and a median duration of intermittent claudication of five years were randomized to either active treatment with Padma 28 or placebo. The effect of treatment was quantified by measurements of systemic and peripheral systolic blood pressures and by measurements of the pain-free and the maximal walking distance on a treadmill. The ankle pressure index (ankle systolic pressure/arm systolic pressure) was calculated. The group randomized to active treatment received two tablets bid containing 340 mg of a dried herbal mixture composed according to an ancient lamaistic preparation (Padma 28). After active treatments, administered over a period of four months in a double-blinded, randomized design, the patients allocated to this group attained a significant increase in the pain-free walking distance from 52 m (20-106) to 86 m (24-164; P <0.05) and in the maximal walking distance from 115 m (72-218) to 227 m (73- > 1,000; P <0.05). The patient-group receiving placebo treatments did not show any significant changes in either the painfree or the maximal walking distance. The authors could not demonstrate any significant changes in the ankle pressure index either during active or during placebo treatment. In conclusion, this study has shown that treatment with Padma 28 over a period of four months significantly increased the walking distance in patients with stable, intermittent claudication of long duration.

M3 - Journal article

VL - 44

SP - 863

EP - 867

JO - Angiology

JF - Angiology

SN - 0003-3197

IS - 11

ER -

ID: 34078894