Forskning ved Københavns Universitet - Københavns Universitet

Forside

A novel PNA-monomer for recognition of thymine in triple-helix structures

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

To expand the triplex recognition repertoire of Nucleic Acids, novel nucleobases that recognize thymine in a T-A base pair are still required. A novel conformationally constrained PNA-monomer (II) capable of binding T in a triplex motif was designed and synthesized in 7 steps starting from commercially available dimethyl 2-oxoglutarate.

OriginalsprogEngelsk
TidsskriftNucleosides, nucleotides & nucleic acids
Vol/bind22
Udgave nummer5-8
Sider (fra-til)1331-1333
Antal sider3
DOI
StatusUdgivet - 21 okt. 2003

ID: 124520