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Activated T lymphocytes disappear from circulation during endotoxemia in humans

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Activated T lymphocytes disappear from circulation during endotoxemia in humans. / Suarez Krabbe, Karen; Kemp, Helle Bruunsgaard; Qvist, Jesper; Fonsmark, Lise; Møller, Kirsten; Hansen, Christian Muff; Skinhøj, Peter; Pedersen, Bente Klarlund.

I: Clinical and Vaccine Immunology, Bind 9, Nr. 3, 31.12.2002, s. 731-735.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Suarez Krabbe, K, Kemp, HB, Qvist, J, Fonsmark, L, Møller, K, Hansen, CM, Skinhøj, P & Pedersen, BK 2002, 'Activated T lymphocytes disappear from circulation during endotoxemia in humans', Clinical and Vaccine Immunology, bind 9, nr. 3, s. 731-735.

APA

Suarez Krabbe, K., Kemp, H. B., Qvist, J., Fonsmark, L., Møller, K., Hansen, C. M., Skinhøj, P., & Pedersen, B. K. (2002). Activated T lymphocytes disappear from circulation during endotoxemia in humans. Clinical and Vaccine Immunology, 9(3), 731-735.

Vancouver

Suarez Krabbe K, Kemp HB, Qvist J, Fonsmark L, Møller K, Hansen CM o.a. Activated T lymphocytes disappear from circulation during endotoxemia in humans. Clinical and Vaccine Immunology. 2002 dec 31;9(3):731-735.

Author

Suarez Krabbe, Karen ; Kemp, Helle Bruunsgaard ; Qvist, Jesper ; Fonsmark, Lise ; Møller, Kirsten ; Hansen, Christian Muff ; Skinhøj, Peter ; Pedersen, Bente Klarlund. / Activated T lymphocytes disappear from circulation during endotoxemia in humans. I: Clinical and Vaccine Immunology. 2002 ; Bind 9, Nr. 3. s. 731-735.

Bibtex

@article{ae7d8c2706b8429bafa002aea3322b9e,
title = "Activated T lymphocytes disappear from circulation during endotoxemia in humans",
abstract = "Seventeen volunteers received an intravenous bolus of endotoxin (2 ng/kg of body weight). Endotoxin-induced lymphopenia was constituted mainly by cells with an immature phenotype (CD45RA(+) CD45RO(-)) that were less likely to undergo apoptosis (CD28(+)), whereas cells with the highest rates of disappearance were characterized by an activated phenotype (CD45RA(-) CD45RO(+)) as well as a phenotype linked to apoptosis (CD95(+) CD28(-)). In conclusion, endotoxin-induced lymphopenia reflects the disappearance from the circulation of activated lymphocytes prone to undergo apoptosis.",
author = "{Suarez Krabbe}, Karen and Kemp, {Helle Bruunsgaard} and Jesper Qvist and Lise Fonsmark and Kirsten M{\o}ller and Hansen, {Christian Muff} and Peter Skinh{\o}j and Pedersen, {Bente Klarlund}",
year = "2002",
month = dec,
day = "31",
language = "Dansk",
volume = "9",
pages = "731--735",
journal = "Clinical and Vaccine Immunology",
issn = "1556-6811",
publisher = "American Society for Microbiology",
number = "3",

}

RIS

TY - JOUR

T1 - Activated T lymphocytes disappear from circulation during endotoxemia in humans

AU - Suarez Krabbe, Karen

AU - Kemp, Helle Bruunsgaard

AU - Qvist, Jesper

AU - Fonsmark, Lise

AU - Møller, Kirsten

AU - Hansen, Christian Muff

AU - Skinhøj, Peter

AU - Pedersen, Bente Klarlund

PY - 2002/12/31

Y1 - 2002/12/31

N2 - Seventeen volunteers received an intravenous bolus of endotoxin (2 ng/kg of body weight). Endotoxin-induced lymphopenia was constituted mainly by cells with an immature phenotype (CD45RA(+) CD45RO(-)) that were less likely to undergo apoptosis (CD28(+)), whereas cells with the highest rates of disappearance were characterized by an activated phenotype (CD45RA(-) CD45RO(+)) as well as a phenotype linked to apoptosis (CD95(+) CD28(-)). In conclusion, endotoxin-induced lymphopenia reflects the disappearance from the circulation of activated lymphocytes prone to undergo apoptosis.

AB - Seventeen volunteers received an intravenous bolus of endotoxin (2 ng/kg of body weight). Endotoxin-induced lymphopenia was constituted mainly by cells with an immature phenotype (CD45RA(+) CD45RO(-)) that were less likely to undergo apoptosis (CD28(+)), whereas cells with the highest rates of disappearance were characterized by an activated phenotype (CD45RA(-) CD45RO(+)) as well as a phenotype linked to apoptosis (CD95(+) CD28(-)). In conclusion, endotoxin-induced lymphopenia reflects the disappearance from the circulation of activated lymphocytes prone to undergo apoptosis.

M3 - Tidsskriftartikel

VL - 9

SP - 731

EP - 735

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

SN - 1556-6811

IS - 3

ER -

ID: 162988992