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Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice

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MicroRNAs are short, endogenous RNA molecules that can bind to parts of target mRNAs, thus inhibiting their translation and causing accelerated turnover or degradation of transcripts, thereby regulating gene expression. Several microRNAs have been found to be upregulated in atopic dermatitis and psoriasis, indicating a role in inflammatory skin diseases. However, there have been no studies on the expression of microRNAs in allergic contact dermatitis.
OriginalsprogEngelsk
BogserieContact Dermatitis. Supplement
Vol/bind67
Udgave nummer5
Sider (fra-til)298-305
Antal sider8
ISSN1396-6669
DOI
StatusUdgivet - nov. 2012

ID: 46484815