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Apixaban versus enoxaparin for thromboprophylaxis after hip replacement

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Michael Rud Lassen
  • Alexander Gallus
  • Gary E Raskob
  • Graham Pineo
  • Dalei Chen
  • Luz Margarita Ramirez
  • ADVANCE-3 Investigators
  • Benn Rønnow Duus
There are various regimens for thromboprophylaxis after hip replacement. Low-molecular-weight heparins such as enoxaparin predominantly inhibit factor Xa but also inhibit thrombin to some degree. Orally active, specific factor Xa inhibitors such as apixaban may provide effective thromboprophylaxis with a lower risk of bleeding and improved ease of use.
OriginalsprogEngelsk
TidsskriftNew England Journal of Medicine
Vol/bind363
Udgave nummer26
Sider (fra-til)2487-98
Antal sider12
ISSN0028-4793
DOI
StatusUdgivet - 23 dec. 2010

ID: 34053104