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Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats

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Essential fatty acid-deficient rats were fed ethyl [U-C]arachidonate (308 dpm/nmol) and when a decrease in the transepidermal water loss was seen, the epidermal sphingolipids, acylglucosylceramide and acylceramide were isolated. [C]Linoleic acid (approx. 130 dpm/nmol) was present in both lipid classes, while the substrate was only detected in the former. These results intimate that in vivo retroconversion of arachidonic to linoleic acid can be induced in the rat.
OriginalsprogEngelsk
TidsskriftB B A - Molecular and Cell Biology of Lipids
Vol/bind878
Udgave nummer2
Sider (fra-til)284-287
Antal sider4
ISSN1388-1981
StatusUdgivet - 1 jan. 1986

ID: 45273606