Forskning ved Københavns Universitet - Københavns Universitet


Awareness of deficits in mild cognitive impairment and Alzheimer's disease: do MCI patients have impaired insight?

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Asmus Vogel
  • Jette Stokholm
  • Anders Gade
  • Birgitte Bo Andersen
  • Anne-Mette Hejl
  • Waldemar, Gunhild
In this study we investigated impaired awareness of cognitive deficits in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Very few studies have addressed this topic, and methodological inconsistencies make the comparison of previous studies difficult. From a prospective research program 36 consecutive patients with mild AD (MMSE above 19), 30 with amnesic MCI and 33 matched controls were examined. Using three methods for awareness assessment we found no significant differences in the level of awareness between MCI and AD. Both groups had impaired awareness and significant heterogeneity in the clinical presentation of awareness. The results demonstrate that subjective memory problems should not be a mandatory prerequisite in suspected dementia or MCI, which makes reports from informants together with thorough clinical interview and observation central when assessing suspected dementia disorders.
TidsskriftDementia and Geriatric Cognitive Disorders
Udgave nummer3
Sider (fra-til)181-7
Antal sider7
StatusUdgivet - 2004

ID: 48606660