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Banking of biological fluids for studies of disease-associated protein biomarkers

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Standard

Banking of biological fluids for studies of disease-associated protein biomarkers. / Rasmussen, Anne-Sofie Schrohl; Würtz, Sidse Ørnbjerg; Kohn, Elise; Banks, Rosamonde E.; Nielsen, Hans Jørgen; Sweep, Fred C.G.J.; Brunner, Nils.

I: Molecular and Cellular Proteomics, Bind 7, Nr. 10, 2008, s. 2061-2066.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Rasmussen, A-SS, Würtz, SØ, Kohn, E, Banks, RE, Nielsen, HJ, Sweep, FCGJ & Brunner, N 2008, 'Banking of biological fluids for studies of disease-associated protein biomarkers', Molecular and Cellular Proteomics, bind 7, nr. 10, s. 2061-2066. https://doi.org/10.1074/mcp.R800010-MCP200

APA

Rasmussen, A-S. S., Würtz, S. Ø., Kohn, E., Banks, R. E., Nielsen, H. J., Sweep, F. C. G. J., & Brunner, N. (2008). Banking of biological fluids for studies of disease-associated protein biomarkers. Molecular and Cellular Proteomics, 7(10), 2061-2066. https://doi.org/10.1074/mcp.R800010-MCP200

Vancouver

Rasmussen A-SS, Würtz SØ, Kohn E, Banks RE, Nielsen HJ, Sweep FCGJ o.a. Banking of biological fluids for studies of disease-associated protein biomarkers. Molecular and Cellular Proteomics. 2008;7(10):2061-2066. https://doi.org/10.1074/mcp.R800010-MCP200

Author

Rasmussen, Anne-Sofie Schrohl ; Würtz, Sidse Ørnbjerg ; Kohn, Elise ; Banks, Rosamonde E. ; Nielsen, Hans Jørgen ; Sweep, Fred C.G.J. ; Brunner, Nils. / Banking of biological fluids for studies of disease-associated protein biomarkers. I: Molecular and Cellular Proteomics. 2008 ; Bind 7, Nr. 10. s. 2061-2066.

Bibtex

@article{807b5450c15511dd8ca2000ea68e967b,
title = "Banking of biological fluids for studies of disease-associated protein biomarkers",
abstract = "With the increasing demand of providing personalized medicine the need for biobanking of biological material from individual patients has increased. Such samples are essential for molecular research aimed at characterizing diseases at several levels ranging from epidemiology and diagnostic and prognostic classification to prediction of response to therapy. Clinically validated biomarkers may provide information to be used for diagnosis, screening, evaluation of risk/predisposition, assessment of prognosis, monitoring (recurrence of disease), and prediction of response to treatment and as a surrogate response marker. Many types of biological fluids or tissues can be collected and stored in biorepositories. Samples of blood can be further processed into plasma and serum, and tissue pieces can be either frozen or fixed in formalin and then embedded into paraffin. The present review focuses on biological fluids, especially serum and plasma, intended for study of protein biomarkers. In biomarker studies the process from the decision to take a sample from an individual to the moment the sample is safely placed in the biobank consists of several phases including collection of samples, transport of the samples, and handling and storage of samples. Critical points in each step important for high quality biomarker studies are described in this review. Failure to develop and adhere to robust standardized protocols may have significant consequences as the quality of the material stored in the biobank as well as conclusions and clinical recommendations based on analysis of such material may be severely affected.",
author = "Rasmussen, {Anne-Sofie Schrohl} and W{\"u}rtz, {Sidse {\O}rnbjerg} and Elise Kohn and Banks, {Rosamonde E.} and Nielsen, {Hans J{\o}rgen} and Sweep, {Fred C.G.J.} and Nils Brunner",
year = "2008",
doi = "10.1074/mcp.R800010-MCP200",
language = "English",
volume = "7",
pages = "2061--2066",
journal = "Molecular and Cellular Proteomics",
issn = "1535-9476",
publisher = "American Society for Biochemistry and Molecular Biology",
number = "10",

}

RIS

TY - JOUR

T1 - Banking of biological fluids for studies of disease-associated protein biomarkers

AU - Rasmussen, Anne-Sofie Schrohl

AU - Würtz, Sidse Ørnbjerg

AU - Kohn, Elise

AU - Banks, Rosamonde E.

AU - Nielsen, Hans Jørgen

AU - Sweep, Fred C.G.J.

AU - Brunner, Nils

PY - 2008

Y1 - 2008

N2 - With the increasing demand of providing personalized medicine the need for biobanking of biological material from individual patients has increased. Such samples are essential for molecular research aimed at characterizing diseases at several levels ranging from epidemiology and diagnostic and prognostic classification to prediction of response to therapy. Clinically validated biomarkers may provide information to be used for diagnosis, screening, evaluation of risk/predisposition, assessment of prognosis, monitoring (recurrence of disease), and prediction of response to treatment and as a surrogate response marker. Many types of biological fluids or tissues can be collected and stored in biorepositories. Samples of blood can be further processed into plasma and serum, and tissue pieces can be either frozen or fixed in formalin and then embedded into paraffin. The present review focuses on biological fluids, especially serum and plasma, intended for study of protein biomarkers. In biomarker studies the process from the decision to take a sample from an individual to the moment the sample is safely placed in the biobank consists of several phases including collection of samples, transport of the samples, and handling and storage of samples. Critical points in each step important for high quality biomarker studies are described in this review. Failure to develop and adhere to robust standardized protocols may have significant consequences as the quality of the material stored in the biobank as well as conclusions and clinical recommendations based on analysis of such material may be severely affected.

AB - With the increasing demand of providing personalized medicine the need for biobanking of biological material from individual patients has increased. Such samples are essential for molecular research aimed at characterizing diseases at several levels ranging from epidemiology and diagnostic and prognostic classification to prediction of response to therapy. Clinically validated biomarkers may provide information to be used for diagnosis, screening, evaluation of risk/predisposition, assessment of prognosis, monitoring (recurrence of disease), and prediction of response to treatment and as a surrogate response marker. Many types of biological fluids or tissues can be collected and stored in biorepositories. Samples of blood can be further processed into plasma and serum, and tissue pieces can be either frozen or fixed in formalin and then embedded into paraffin. The present review focuses on biological fluids, especially serum and plasma, intended for study of protein biomarkers. In biomarker studies the process from the decision to take a sample from an individual to the moment the sample is safely placed in the biobank consists of several phases including collection of samples, transport of the samples, and handling and storage of samples. Critical points in each step important for high quality biomarker studies are described in this review. Failure to develop and adhere to robust standardized protocols may have significant consequences as the quality of the material stored in the biobank as well as conclusions and clinical recommendations based on analysis of such material may be severely affected.

U2 - 10.1074/mcp.R800010-MCP200

DO - 10.1074/mcp.R800010-MCP200

M3 - Journal article

C2 - 18676364

VL - 7

SP - 2061

EP - 2066

JO - Molecular and Cellular Proteomics

JF - Molecular and Cellular Proteomics

SN - 1535-9476

IS - 10

ER -

ID: 8834157