Forskning ved Københavns Universitet - Københavns Universitet

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Behandling af svær astma med biologiske lægemidler hos børn og unge

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Prerequisites for successful treatment of severe asthma in children and adolescents with biological drugs are: 1) systematic assessment, excluding and treating other causes of lack of asthma control, 2) immunological phenotyping of the patient, and 3) choice of biological drug targeting the specific disease mechanism. Anti-immunoglobulin (Ig) E and anti-interleukin (IL)-5 have a clinically relevant effect reducing exacerbation rate, but there is still a need for studies in children and adolescents being treated with anti-IgE and anti-IL-5 as well as newer biological drugs, which affect lung function, asthma control and quality of life.

OriginalsprogDansk
ArtikelnummerV05180364
TidsskriftUgeskrift for Laeger
Vol/bind181
Antal sider5
ISSN0041-5782
StatusUdgivet - 2019

    Forskningsområder

  • Adolescent, Anti-Asthmatic Agents/therapeutic use, Antibodies, Monoclonal, Humanized, Asthma/drug therapy, Biological Products/therapeutic use, Child, Humans, Omalizumab, Quality of Life

ID: 240953435