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Biglycan deficiency interferes with ovariectomy-induced bone loss

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Karina L Nielsen
  • Matthew R Allen
  • Susan A Bloomfield
  • Thomas L Andersen
  • Xiao-Dong Chen
  • Hans S Poulsen
  • Marian F Young
  • Heegaard, Anne-Marie
Biglycan is a matrix proteoglycan with a possible role in bone turnover. In a 4-week study with sham-operated or OVX biglycan-deficient or wildtype mice, we show that biglycan-deficient mice are resistant to OVX-induced trabecular bone loss and that there is a gender difference in the response to biglycan deficiency.
OriginalsprogEngelsk
TidsskriftJournal of Bone and Mineral Research
Vol/bind18
Udgave nummer12
Sider (fra-til)2152-8
Antal sider7
ISSN0884-0431
DOI
StatusUdgivet - 2003

ID: 38426449