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Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans. / Rasmussen, Peter; Kim, Yu-Sok; Krogh-Madsen, Rikke; Lundby, Carsten; Olsen, Niels Vidiendal; Secher, Niels H; van Lieshout, Johannes J.

I: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Bind 26, Nr. 3, 03.2012, s. 1343-8.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Rasmussen, P, Kim, Y-S, Krogh-Madsen, R, Lundby, C, Olsen, NV, Secher, NH & van Lieshout, JJ 2012, 'Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans', FASEB journal : official publication of the Federation of American Societies for Experimental Biology, bind 26, nr. 3, s. 1343-8. https://doi.org/10.1096/fj.11-193508

APA

Rasmussen, P., Kim, Y-S., Krogh-Madsen, R., Lundby, C., Olsen, N. V., Secher, N. H., & van Lieshout, J. J. (2012). Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 26(3), 1343-8. https://doi.org/10.1096/fj.11-193508

Vancouver

Rasmussen P, Kim Y-S, Krogh-Madsen R, Lundby C, Olsen NV, Secher NH o.a. Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 mar;26(3):1343-8. https://doi.org/10.1096/fj.11-193508

Author

Rasmussen, Peter ; Kim, Yu-Sok ; Krogh-Madsen, Rikke ; Lundby, Carsten ; Olsen, Niels Vidiendal ; Secher, Niels H ; van Lieshout, Johannes J. / Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans. I: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 ; Bind 26, Nr. 3. s. 1343-8.

Bibtex

@article{74b85784b34146cfb88ea663dc261d0b,
title = "Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans",
abstract = "Administration of erythropoietin (EPO) has been linked to cerebrovascular events. EPO reduces vascular conductance, possibly because of the increase in hematocrit. Whether EPO in itself affects the vasculature remains unknown; here it was evaluated in healthy males by determining systemic and cerebrovascular variables following acute (30,000 IU/d for 3 d; n=8) and chronic (5000 IU/week for 13 wk; n=8) administration of EPO, while the responsiveness of the vasculature was challenged during cycling exercise, with and without hypoxia. Prolonged administration of EPO increased hematocrit from 42.5 ± 3.7 to 47.6 ± 4.1% (P",
keywords = "Adult, Blood Flow Velocity, Blood Pressure, Cerebrovascular Circulation, Cross-Over Studies, Double-Blind Method, Erythropoietin, Exercise, Hematocrit, Homeostasis, Humans, Injections, Intravenous, Injections, Subcutaneous, Male, Oxygen, Oxygen Consumption, Time Factors, Vasoconstriction, Young Adult",
author = "Peter Rasmussen and Yu-Sok Kim and Rikke Krogh-Madsen and Carsten Lundby and Olsen, {Niels Vidiendal} and Secher, {Niels H} and {van Lieshout}, {Johannes J}",
year = "2012",
month = mar,
doi = "10.1096/fj.11-193508",
language = "English",
volume = "26",
pages = "1343--8",
journal = "F A S E B Journal",
issn = "0892-6638",
publisher = "Federation of American Societies for Experimental Biology",
number = "3",

}

RIS

TY - JOUR

T1 - Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans

AU - Rasmussen, Peter

AU - Kim, Yu-Sok

AU - Krogh-Madsen, Rikke

AU - Lundby, Carsten

AU - Olsen, Niels Vidiendal

AU - Secher, Niels H

AU - van Lieshout, Johannes J

PY - 2012/3

Y1 - 2012/3

N2 - Administration of erythropoietin (EPO) has been linked to cerebrovascular events. EPO reduces vascular conductance, possibly because of the increase in hematocrit. Whether EPO in itself affects the vasculature remains unknown; here it was evaluated in healthy males by determining systemic and cerebrovascular variables following acute (30,000 IU/d for 3 d; n=8) and chronic (5000 IU/week for 13 wk; n=8) administration of EPO, while the responsiveness of the vasculature was challenged during cycling exercise, with and without hypoxia. Prolonged administration of EPO increased hematocrit from 42.5 ± 3.7 to 47.6 ± 4.1% (P

AB - Administration of erythropoietin (EPO) has been linked to cerebrovascular events. EPO reduces vascular conductance, possibly because of the increase in hematocrit. Whether EPO in itself affects the vasculature remains unknown; here it was evaluated in healthy males by determining systemic and cerebrovascular variables following acute (30,000 IU/d for 3 d; n=8) and chronic (5000 IU/week for 13 wk; n=8) administration of EPO, while the responsiveness of the vasculature was challenged during cycling exercise, with and without hypoxia. Prolonged administration of EPO increased hematocrit from 42.5 ± 3.7 to 47.6 ± 4.1% (P

KW - Adult

KW - Blood Flow Velocity

KW - Blood Pressure

KW - Cerebrovascular Circulation

KW - Cross-Over Studies

KW - Double-Blind Method

KW - Erythropoietin

KW - Exercise

KW - Hematocrit

KW - Homeostasis

KW - Humans

KW - Injections, Intravenous

KW - Injections, Subcutaneous

KW - Male

KW - Oxygen

KW - Oxygen Consumption

KW - Time Factors

KW - Vasoconstriction

KW - Young Adult

U2 - 10.1096/fj.11-193508

DO - 10.1096/fj.11-193508

M3 - Journal article

C2 - 22159148

VL - 26

SP - 1343

EP - 1348

JO - F A S E B Journal

JF - F A S E B Journal

SN - 0892-6638

IS - 3

ER -

ID: 47239568