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Cancer systems biology: Harnessing off-target effects

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

  • Gaye Saginc
  • Franziska Voellmy
  • Rune Linding
The 'off-targets' of a drug are often poorly characterized yet could be harnessed in the treatment of complex diseases. A recent study used a small-molecule screening in non-small-cell lung cancer to repurpose an FDA-approved ALK/IGF1R inhibitor and uncover its mechanism of action
OriginalsprogEngelsk
TidsskriftNature Chemical Biology
Vol/bind13
Udgave nummer12
Sider (fra-til)1204-1205
Antal sider2
ISSN1552-4450
DOI
StatusUdgivet - 21 nov. 2017

ID: 186635336