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Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

The majority of testicular germ cell cancers develop through a pre-invasive carcinoma in situ (CIS) stage. The CIS cell is a neoplastic counterpart of foetal germ cells. During their development, foetal germ cells undergo extensive and essential epigenetic modifications, but little is known about epigenetic patterns in CIS cells.
OriginalsprogEngelsk
TidsskriftBritish Journal of Cancer
Vol/bind103
Udgave nummer8
Sider (fra-til)1269-76
Antal sider8
ISSN0007-0920
DOI
StatusUdgivet - 12 okt. 2010

ID: 34118424