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Characterization of riboflavin-photosensitized changes in aqueous solutions of alginate by dynamic light scattering

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Standard

Characterization of riboflavin-photosensitized changes in aqueous solutions of alginate by dynamic light scattering. / Kjøniksen, Anna-Lena; Baldursdottir, Stefania G.; Nyström, Bo.

I: Macromolecular Bioscience, Bind 4, Nr. 2, 20.02.2004, s. 76-83.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Kjøniksen, A-L, Baldursdottir, SG & Nyström, B 2004, 'Characterization of riboflavin-photosensitized changes in aqueous solutions of alginate by dynamic light scattering', Macromolecular Bioscience, bind 4, nr. 2, s. 76-83. https://doi.org/10.1002/mabi.200300048

APA

Kjøniksen, A-L., Baldursdottir, S. G., & Nyström, B. (2004). Characterization of riboflavin-photosensitized changes in aqueous solutions of alginate by dynamic light scattering. Macromolecular Bioscience, 4(2), 76-83. https://doi.org/10.1002/mabi.200300048

Vancouver

Kjøniksen A-L, Baldursdottir SG, Nyström B. Characterization of riboflavin-photosensitized changes in aqueous solutions of alginate by dynamic light scattering. Macromolecular Bioscience. 2004 feb 20;4(2):76-83. https://doi.org/10.1002/mabi.200300048

Author

Kjøniksen, Anna-Lena ; Baldursdottir, Stefania G. ; Nyström, Bo. / Characterization of riboflavin-photosensitized changes in aqueous solutions of alginate by dynamic light scattering. I: Macromolecular Bioscience. 2004 ; Bind 4, Nr. 2. s. 76-83.

Bibtex

@article{d04ce105d0d946a8a1829cd9e34bab80,
title = "Characterization of riboflavin-photosensitized changes in aqueous solutions of alginate by dynamic light scattering",
abstract = "The effect of irradiation, in the wavelength range of 310-800 nm, on aqueous solutions (pH = 7.4) of alginate in the presence of the photosensitizer riboflavin (RF) has been investigated with the aid of dynamic light scattering (DLS). Under aerobic conditions light irradiation of RF causes scission of the polymer chains which affects the polymer dynamics. The time correlation data obtained from DLS experiments showed at all conditions the existence of two relaxation modes: one single exponential at short times, followed by a stretched exponential at longer times. The slow relaxation time revealed, over the whole considered concentration range, lower values for the alginate/RF system, whereas no effect of photochemical degradation was observed for the fast relaxation time in the semidilute regime. The results suggest that the photochemically induced fragmentation of alginate affects the slow relaxation mode, associated with disengagement relaxation of individual chains or cluster relaxation, in a similar way as the zero-shear viscosity. These findings provide detailed insight into the dynamics of the polymer matrix, and this knowledge can be useful in the context of controlled-release delivery of drugs. The chemical units of alginate (M = mannuronic acid and G = guluronic acid).",
author = "Anna-Lena Kj{\o}niksen and Baldursdottir, {Stefania G.} and Bo Nystr{\"o}m",
year = "2004",
month = "2",
day = "20",
doi = "10.1002/mabi.200300048",
language = "English",
volume = "4",
pages = "76--83",
journal = "Macromolecular Bioscience",
issn = "1616-5187",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "2",

}

RIS

TY - JOUR

T1 - Characterization of riboflavin-photosensitized changes in aqueous solutions of alginate by dynamic light scattering

AU - Kjøniksen, Anna-Lena

AU - Baldursdottir, Stefania G.

AU - Nyström, Bo

PY - 2004/2/20

Y1 - 2004/2/20

N2 - The effect of irradiation, in the wavelength range of 310-800 nm, on aqueous solutions (pH = 7.4) of alginate in the presence of the photosensitizer riboflavin (RF) has been investigated with the aid of dynamic light scattering (DLS). Under aerobic conditions light irradiation of RF causes scission of the polymer chains which affects the polymer dynamics. The time correlation data obtained from DLS experiments showed at all conditions the existence of two relaxation modes: one single exponential at short times, followed by a stretched exponential at longer times. The slow relaxation time revealed, over the whole considered concentration range, lower values for the alginate/RF system, whereas no effect of photochemical degradation was observed for the fast relaxation time in the semidilute regime. The results suggest that the photochemically induced fragmentation of alginate affects the slow relaxation mode, associated with disengagement relaxation of individual chains or cluster relaxation, in a similar way as the zero-shear viscosity. These findings provide detailed insight into the dynamics of the polymer matrix, and this knowledge can be useful in the context of controlled-release delivery of drugs. The chemical units of alginate (M = mannuronic acid and G = guluronic acid).

AB - The effect of irradiation, in the wavelength range of 310-800 nm, on aqueous solutions (pH = 7.4) of alginate in the presence of the photosensitizer riboflavin (RF) has been investigated with the aid of dynamic light scattering (DLS). Under aerobic conditions light irradiation of RF causes scission of the polymer chains which affects the polymer dynamics. The time correlation data obtained from DLS experiments showed at all conditions the existence of two relaxation modes: one single exponential at short times, followed by a stretched exponential at longer times. The slow relaxation time revealed, over the whole considered concentration range, lower values for the alginate/RF system, whereas no effect of photochemical degradation was observed for the fast relaxation time in the semidilute regime. The results suggest that the photochemically induced fragmentation of alginate affects the slow relaxation mode, associated with disengagement relaxation of individual chains or cluster relaxation, in a similar way as the zero-shear viscosity. These findings provide detailed insight into the dynamics of the polymer matrix, and this knowledge can be useful in the context of controlled-release delivery of drugs. The chemical units of alginate (M = mannuronic acid and G = guluronic acid).

U2 - 10.1002/mabi.200300048

DO - 10.1002/mabi.200300048

M3 - Journal article

C2 - 15468197

VL - 4

SP - 76

EP - 83

JO - Macromolecular Bioscience

JF - Macromolecular Bioscience

SN - 1616-5187

IS - 2

ER -

ID: 44565541