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Continuous vs stepwise anal acoustic reflectometry: An improved technique for physiological measurement of anal sphincter function?

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Continuous vs stepwise anal acoustic reflectometry : An improved technique for physiological measurement of anal sphincter function? / Heywood, Nick A; Nicholson, James E; Sharma, Abhiram; Kiff, Ed S; Klarskov, Niels; Telford, Karen J.

I: Neurourology and Urodynamics, Bind 39, Nr. 1, 2020, s. 447-454.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Heywood, NA, Nicholson, JE, Sharma, A, Kiff, ES, Klarskov, N & Telford, KJ 2020, 'Continuous vs stepwise anal acoustic reflectometry: An improved technique for physiological measurement of anal sphincter function?', Neurourology and Urodynamics, bind 39, nr. 1, s. 447-454. https://doi.org/10.1002/nau.24235

APA

Heywood, N. A., Nicholson, J. E., Sharma, A., Kiff, E. S., Klarskov, N., & Telford, K. J. (2020). Continuous vs stepwise anal acoustic reflectometry: An improved technique for physiological measurement of anal sphincter function? Neurourology and Urodynamics, 39(1), 447-454. https://doi.org/10.1002/nau.24235

Vancouver

Heywood NA, Nicholson JE, Sharma A, Kiff ES, Klarskov N, Telford KJ. Continuous vs stepwise anal acoustic reflectometry: An improved technique for physiological measurement of anal sphincter function? Neurourology and Urodynamics. 2020;39(1):447-454. https://doi.org/10.1002/nau.24235

Author

Heywood, Nick A ; Nicholson, James E ; Sharma, Abhiram ; Kiff, Ed S ; Klarskov, Niels ; Telford, Karen J. / Continuous vs stepwise anal acoustic reflectometry : An improved technique for physiological measurement of anal sphincter function?. I: Neurourology and Urodynamics. 2020 ; Bind 39, Nr. 1. s. 447-454.

Bibtex

@article{70cd7830fe674dd895f330ad6c92c6e8,
title = "Continuous vs stepwise anal acoustic reflectometry: An improved technique for physiological measurement of anal sphincter function?",
abstract = "BACKGROUND: Anal acoustic reflectometry (AAR) is a technique for measuring the physiological profile of the anal canal, primarily the internal anal sphincter. Evaluation of a new continuous method, recently developed for the urethra, would enable its future application for investigation of rectal reflexes.METHODS: Patients aged 18 and over with fecal incontinence (FI) were included. Stepwise AAR parameters were compared with continuous opening pressure (Op, cmH2 O), opening elastance (Oe, cmH2 O/mm2 ), closing pressure (Cp, cmH2 O), closing elastance (Ce, cmH2 O/mm2 ), hysteresis (Hys, [%]), squeeze opening pressure (SqOp, cmH2 O), and squeeze opening elastance (SqOe, cmH2 O/mm2 ). Vaizey incontinence and Manchester Health Questionnaire scores were also collected.RESULTS: Thirty-two patients, 26 females were analyzed. Median age: 60 (range, 32-75). Median AAR parameters of Op (37.50 vs 35.15, P = .031), Oe (1.31 vs 0.84, P < .0001), Ce (1.11 vs 0.88, P < .0001), Hys (37.75 vs 19.04, P < .0001), and SqOe (1.27 vs 1.06, P = .005) were significantly higher with the continuous method. Cp (22.70 vs 27.22, P = .003) is lower and SqOp (96.87 vs 59.47, P = .71) not significantly different. The continuous technique had superior repeatability between cycles for all AAR parameters except Oe, which was equivalent and continuous SqOp had a stronger negative correlation with Vaizey score than stepwise (-0.46, P = .009 vs -0.37, P = .038).CONCLUSIONS: The differences seen between the two techniques are likely to be related to the rate of stretch. The continuous technique appears to represent a more physiological measurement of anal sphincter function than the stepwise technique particularly in the assessment of voluntary squeeze function.",
keywords = "Adult, Aged, Anal Canal/physiopathology, Anus Diseases/diagnosis, Fecal Incontinence/physiopathology, Female, Humans, Male, Manometry/methods, Middle Aged, Rectum/physiopathology, Reflex/physiology",
author = "Heywood, {Nick A} and Nicholson, {James E} and Abhiram Sharma and Kiff, {Ed S} and Niels Klarskov and Telford, {Karen J}",
note = "{\textcopyright} 2019 Wiley Periodicals, Inc.",
year = "2020",
doi = "10.1002/nau.24235",
language = "English",
volume = "39",
pages = "447--454",
journal = "Neurourology and Urodynamics",
issn = "0733-2467",
publisher = "JohnWiley & Sons, Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Continuous vs stepwise anal acoustic reflectometry

T2 - An improved technique for physiological measurement of anal sphincter function?

AU - Heywood, Nick A

AU - Nicholson, James E

AU - Sharma, Abhiram

AU - Kiff, Ed S

AU - Klarskov, Niels

AU - Telford, Karen J

N1 - © 2019 Wiley Periodicals, Inc.

PY - 2020

Y1 - 2020

N2 - BACKGROUND: Anal acoustic reflectometry (AAR) is a technique for measuring the physiological profile of the anal canal, primarily the internal anal sphincter. Evaluation of a new continuous method, recently developed for the urethra, would enable its future application for investigation of rectal reflexes.METHODS: Patients aged 18 and over with fecal incontinence (FI) were included. Stepwise AAR parameters were compared with continuous opening pressure (Op, cmH2 O), opening elastance (Oe, cmH2 O/mm2 ), closing pressure (Cp, cmH2 O), closing elastance (Ce, cmH2 O/mm2 ), hysteresis (Hys, [%]), squeeze opening pressure (SqOp, cmH2 O), and squeeze opening elastance (SqOe, cmH2 O/mm2 ). Vaizey incontinence and Manchester Health Questionnaire scores were also collected.RESULTS: Thirty-two patients, 26 females were analyzed. Median age: 60 (range, 32-75). Median AAR parameters of Op (37.50 vs 35.15, P = .031), Oe (1.31 vs 0.84, P < .0001), Ce (1.11 vs 0.88, P < .0001), Hys (37.75 vs 19.04, P < .0001), and SqOe (1.27 vs 1.06, P = .005) were significantly higher with the continuous method. Cp (22.70 vs 27.22, P = .003) is lower and SqOp (96.87 vs 59.47, P = .71) not significantly different. The continuous technique had superior repeatability between cycles for all AAR parameters except Oe, which was equivalent and continuous SqOp had a stronger negative correlation with Vaizey score than stepwise (-0.46, P = .009 vs -0.37, P = .038).CONCLUSIONS: The differences seen between the two techniques are likely to be related to the rate of stretch. The continuous technique appears to represent a more physiological measurement of anal sphincter function than the stepwise technique particularly in the assessment of voluntary squeeze function.

AB - BACKGROUND: Anal acoustic reflectometry (AAR) is a technique for measuring the physiological profile of the anal canal, primarily the internal anal sphincter. Evaluation of a new continuous method, recently developed for the urethra, would enable its future application for investigation of rectal reflexes.METHODS: Patients aged 18 and over with fecal incontinence (FI) were included. Stepwise AAR parameters were compared with continuous opening pressure (Op, cmH2 O), opening elastance (Oe, cmH2 O/mm2 ), closing pressure (Cp, cmH2 O), closing elastance (Ce, cmH2 O/mm2 ), hysteresis (Hys, [%]), squeeze opening pressure (SqOp, cmH2 O), and squeeze opening elastance (SqOe, cmH2 O/mm2 ). Vaizey incontinence and Manchester Health Questionnaire scores were also collected.RESULTS: Thirty-two patients, 26 females were analyzed. Median age: 60 (range, 32-75). Median AAR parameters of Op (37.50 vs 35.15, P = .031), Oe (1.31 vs 0.84, P < .0001), Ce (1.11 vs 0.88, P < .0001), Hys (37.75 vs 19.04, P < .0001), and SqOe (1.27 vs 1.06, P = .005) were significantly higher with the continuous method. Cp (22.70 vs 27.22, P = .003) is lower and SqOp (96.87 vs 59.47, P = .71) not significantly different. The continuous technique had superior repeatability between cycles for all AAR parameters except Oe, which was equivalent and continuous SqOp had a stronger negative correlation with Vaizey score than stepwise (-0.46, P = .009 vs -0.37, P = .038).CONCLUSIONS: The differences seen between the two techniques are likely to be related to the rate of stretch. The continuous technique appears to represent a more physiological measurement of anal sphincter function than the stepwise technique particularly in the assessment of voluntary squeeze function.

KW - Adult

KW - Aged

KW - Anal Canal/physiopathology

KW - Anus Diseases/diagnosis

KW - Fecal Incontinence/physiopathology

KW - Female

KW - Humans

KW - Male

KW - Manometry/methods

KW - Middle Aged

KW - Rectum/physiopathology

KW - Reflex/physiology

U2 - 10.1002/nau.24235

DO - 10.1002/nau.24235

M3 - Journal article

C2 - 31770467

VL - 39

SP - 447

EP - 454

JO - Neurourology and Urodynamics

JF - Neurourology and Urodynamics

SN - 0733-2467

IS - 1

ER -

ID: 256326377