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Cover picture: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds

Publikation: FormidlingTidsskriftartikel

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Direct C−H difluoromethylation of electron-deficient positions in nitrogen-containing heterocycles is attained by difluoromethyl radicals generated in-situ from difluoroacetic acid under silver-catalyzed oxidative decarboxylation. Control of the reaction temperature permits either mono- or disubstitution. More information can be found in the Communication by J. Nielsen et al. (DOI: 10.1002/chem.201704261).
OriginalsprogEngelsk
TidsskriftChemistry - A European Journal
ISSN0947-6539
StatusUdgivet - 25 okt. 2017

ID: 185005538