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Delayed response of the retina after hyperbaric oxygen exposure

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Delayed response of the retina after hyperbaric oxygen exposure. / Kofoed, Peter Kristian; Hasler, Pascal W; Sander, Birgit; Jansen, Erik C; Klemp, Kristian; Larsen, Michael.

I: Acta Ophthamologica (Online), Bind 89, Nr. 8, 2011, s. 774-778.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Kofoed, PK, Hasler, PW, Sander, B, Jansen, EC, Klemp, K & Larsen, M 2011, 'Delayed response of the retina after hyperbaric oxygen exposure', Acta Ophthamologica (Online), bind 89, nr. 8, s. 774-778. https://doi.org/10.1111/j.1755-3768.2009.01832.x, https://doi.org/10.1111/j.1755-3768.2009.01832.x

APA

Kofoed, P. K., Hasler, P. W., Sander, B., Jansen, E. C., Klemp, K., & Larsen, M. (2011). Delayed response of the retina after hyperbaric oxygen exposure. Acta Ophthamologica (Online), 89(8), 774-778. https://doi.org/10.1111/j.1755-3768.2009.01832.x, https://doi.org/10.1111/j.1755-3768.2009.01832.x

Vancouver

Kofoed PK, Hasler PW, Sander B, Jansen EC, Klemp K, Larsen M. Delayed response of the retina after hyperbaric oxygen exposure. Acta Ophthamologica (Online). 2011;89(8):774-778. https://doi.org/10.1111/j.1755-3768.2009.01832.x, https://doi.org/10.1111/j.1755-3768.2009.01832.x

Author

Kofoed, Peter Kristian ; Hasler, Pascal W ; Sander, Birgit ; Jansen, Erik C ; Klemp, Kristian ; Larsen, Michael. / Delayed response of the retina after hyperbaric oxygen exposure. I: Acta Ophthamologica (Online). 2011 ; Bind 89, Nr. 8. s. 774-778.

Bibtex

@article{7c7c2c593d9b47be8d327b2f1157474d,
title = "Delayed response of the retina after hyperbaric oxygen exposure",
abstract = "Purpose: To examine retinal electrophysiological function and retinal thickness in healthy eyes before and after hyperbaric oxygen (HBO) exposure. Methods: The healthy eye in each of six subjects who underwent experimental HBO treatment for branch retinal vein occlusion in the fellow eye was examined using multifocal electroretinography (mfERG) and optical coherence tomography (OCT) at baseline and following a course of five consecutive daily sessions of exposure to HBO at 2.4 atmospheres of absolute pressure lasting 90 min each. Results: After HBO, P1 implicit times of the mfERG were significantly shorter than at baseline. The response was delayed, being undetectable on the day treatment concluded, whereas a 2.65{\%} reduction in implicit time was seen 1 week later (p = 0.032). The P1 implicit time remained 2.49{\%} shorter than at baseline 1 month after the end of the HBO sessions (p = 0.020). The bulk of the response to HBO was found in the foveal and parafoveal regions. No detectable change was seen in mfERG amplitudes or in the volume or thickness of the retina. Conclusion: A mfERG component related to bipolar and M{\"u}ller cell function was accelerated by a short intermittent exposure to HBO. The response developed after the end of the HBO exposure and lasted for at least 3 weeks, suggesting that it was prompted by the withdrawal of HBO rather than the onset and subsequent brief exposure to HBO.",
author = "Kofoed, {Peter Kristian} and Hasler, {Pascal W} and Birgit Sander and Jansen, {Erik C} and Kristian Klemp and Michael Larsen",
year = "2011",
doi = "10.1111/j.1755-3768.2009.01832.x",
language = "English",
volume = "89",
pages = "774--778",
journal = "Acta Ophthalmologica",
issn = "1755-375X",
publisher = "Wiley-Blackwell",
number = "8",

}

RIS

TY - JOUR

T1 - Delayed response of the retina after hyperbaric oxygen exposure

AU - Kofoed, Peter Kristian

AU - Hasler, Pascal W

AU - Sander, Birgit

AU - Jansen, Erik C

AU - Klemp, Kristian

AU - Larsen, Michael

PY - 2011

Y1 - 2011

N2 - Purpose: To examine retinal electrophysiological function and retinal thickness in healthy eyes before and after hyperbaric oxygen (HBO) exposure. Methods: The healthy eye in each of six subjects who underwent experimental HBO treatment for branch retinal vein occlusion in the fellow eye was examined using multifocal electroretinography (mfERG) and optical coherence tomography (OCT) at baseline and following a course of five consecutive daily sessions of exposure to HBO at 2.4 atmospheres of absolute pressure lasting 90 min each. Results: After HBO, P1 implicit times of the mfERG were significantly shorter than at baseline. The response was delayed, being undetectable on the day treatment concluded, whereas a 2.65% reduction in implicit time was seen 1 week later (p = 0.032). The P1 implicit time remained 2.49% shorter than at baseline 1 month after the end of the HBO sessions (p = 0.020). The bulk of the response to HBO was found in the foveal and parafoveal regions. No detectable change was seen in mfERG amplitudes or in the volume or thickness of the retina. Conclusion: A mfERG component related to bipolar and Müller cell function was accelerated by a short intermittent exposure to HBO. The response developed after the end of the HBO exposure and lasted for at least 3 weeks, suggesting that it was prompted by the withdrawal of HBO rather than the onset and subsequent brief exposure to HBO.

AB - Purpose: To examine retinal electrophysiological function and retinal thickness in healthy eyes before and after hyperbaric oxygen (HBO) exposure. Methods: The healthy eye in each of six subjects who underwent experimental HBO treatment for branch retinal vein occlusion in the fellow eye was examined using multifocal electroretinography (mfERG) and optical coherence tomography (OCT) at baseline and following a course of five consecutive daily sessions of exposure to HBO at 2.4 atmospheres of absolute pressure lasting 90 min each. Results: After HBO, P1 implicit times of the mfERG were significantly shorter than at baseline. The response was delayed, being undetectable on the day treatment concluded, whereas a 2.65% reduction in implicit time was seen 1 week later (p = 0.032). The P1 implicit time remained 2.49% shorter than at baseline 1 month after the end of the HBO sessions (p = 0.020). The bulk of the response to HBO was found in the foveal and parafoveal regions. No detectable change was seen in mfERG amplitudes or in the volume or thickness of the retina. Conclusion: A mfERG component related to bipolar and Müller cell function was accelerated by a short intermittent exposure to HBO. The response developed after the end of the HBO exposure and lasted for at least 3 weeks, suggesting that it was prompted by the withdrawal of HBO rather than the onset and subsequent brief exposure to HBO.

U2 - 10.1111/j.1755-3768.2009.01832.x

DO - 10.1111/j.1755-3768.2009.01832.x

M3 - Journal article

C2 - 20064112

VL - 89

SP - 774

EP - 778

JO - Acta Ophthalmologica

JF - Acta Ophthalmologica

SN - 1755-375X

IS - 8

ER -

ID: 34082782