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Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Fungus-growing ants engage in mutualistic associations with both the fungus they cultivate for food and actinobacteria (Pseudonocardia spp.) that produce selective antibiotics to defend that fungus from specialized fungal parasites. We have analyzed one such system at the molecular level and found that the bacterium associated with the ant Apterostigma dentigerum produces dentigerumycin, a cyclic depsipeptide with highly modified amino acids, to selectively inhibit the associated parasitic fungus (Escovopsis sp.).
OriginalsprogEngelsk
TidsskriftNature Chemical Biology
Vol/bind5
Udgave nummer6
Sider (fra-til)391-3
Antal sider3
ISSN1552-4450
DOI
StatusUdgivet - 1 jun. 2009

ID: 33079688