Forskning ved Københavns Universitet - Københavns Universitet

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Der er dokumenteret effekt af ekstrakorporal fotoferese ved T-celle-medierede sygdomme

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Kristian Kofoed
  • Ida Schiødt
  • Robert Gniadecki
During extra corporeal photopheresis (ECP) 1.500 ml blood is extracted. Leucocytes are separated by centrifugation. Methoxsalen is added to the leucocytes and activated by UVA light. After treatment leucocytes are returned to the patient. ECP is a part of the treatment of acute and chronic graft-versus-host disease (GVHD) in bone marrow transplant patients and severe cutaneous T-cell lymphomas (CTLC). Studies have documented an effect of ECP in GVHD and CTLC. ECP has been used to treat other T-cell mediated diseases, the documentation however is sparse. The side effects of ECP are few and not serious.
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind173
Udgave nummer26
Sider (fra-til)1869-74
Antal sider6
ISSN0041-5782
StatusUdgivet - 2011

ID: 40156623