Forskning ved Københavns Universitet - Københavns Universitet


Determination of ivermectin efficacy against cyathostomins and Parascaris equorum on horse farms using selective therapy

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Ivermectin resistance has recently been described in Parascaris equorum and there have been reports
from several countries of a shortened egg reappearance period (ERP) following ivermectin treatment
for cyathostomins. This study was aimed at determining the efficacy of ivermectin in treating cyathostomins
and P. equorum in Danish horses. A total of 196 animals were selected from 52 farms, all of which
were using a selective anthelmintic treatment strategy. ERP was investigated with weekly samples from
96 horses from nine farms. Horses were treated with ivermectin oral paste by their owners at an estimated
dose rate of 0.2 mg/kg. Overall, faecal egg counts were reduced 10–14 days after treatment by
96.9% and 100% for P. equorum and cyathostomins, respectively. Mean faecal egg count reductions at 4
and 6 weeks post treatment were 99.5% and 96.9%, respectively. No signs of developing ivermectin resistance
were found in either cyathostomins or P. equorum in the studied horses.
TidsskriftVeterinary Journal
Udgave nummer1
Sider (fra-til)44-47
Antal sider4
StatusUdgivet - 2011

ID: 32985846