Forskning ved Københavns Universitet - Københavns Universitet

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Diagnostic microbiology in veterinary dermatology: present and future

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

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Background
The microbiology laboratory can be perceived as a service provider rather than an integral part of the healthcare team.

Objectives
The aim of this review is to discuss the current challenges of providing a state-of-the-art diagnostic veterinary microbiology service including the identification (ID) and antimicrobial susceptibility testing (AST) of key pathogens in veterinary dermatology.

Methods
The Study Group for Veterinary Microbiology (ESGVM) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) identified scientific, technological, educational and regulatory issues impacting the predictive value of AST and the quality of the service offered by microbiology laboratories.

Results
The advent of mass spectrometry has significantly reduced the time required for ID of key pathogens such as Staphylococcus pseudintermedius. However, the turnaround time for validated AST methods has remained unchanged for many years. Beyond scientific and technological constraints, AST methods are not harmonized and clinical breakpoints for some antimicrobial drugs are either missing or inadequate. Small laboratories, including in-clinic laboratories, are usually not adequately equipped to run up-to-date clinical microbiologic diagnostic tests.

Conclusions and clinical importance
ESGVM recommends the use of laboratories employing mass spectrometry for ID and broth micro-dilution for AST, and offering assistance by expert microbiologists on pre- and post-analytical issues. Setting general standards for veterinary clinical microbiology, promoting antimicrobial stewardship, and the development of new, validated and rapid diagnostic methods, especially for AST, are among the missions of ESGVM.
OriginalsprogEngelsk
TidsskriftVeterinary Dermatology
Vol/bind28
Udgave nummer1
Sider (fra-til)146–e30
Antal sider12
ISSN0959-4493
DOI
StatusUdgivet - feb. 2017

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