Forskning ved Københavns Universitet - Københavns Universitet

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Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Calcitonin gene-related peptide (CGRP) and its receptor are widely distributed within the circulation and the mechanism behind its vasodilation not only differs from one animal species to another but is also dependent on the type and size of vessel. The present study examines the nature of CGRP-induced vasodilation, characteristics of the CGRP receptor antagonist telcagepant and localization of the key components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) of the CGRP receptor in human subcutaneous arteries.
OriginalsprogEngelsk
TidsskriftActa Physiologica (Print)
Vol/bind210
Udgave nummer4
Sider (fra-til)811-22
Antal sider12
ISSN1748-1708
DOI
StatusUdgivet - apr. 2014

ID: 106213297