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Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest : a nationwide study. / Tranberg, Tinne; Lippert, Freddy K; Christensen, Erika Frischknecht; Stengaard, Carsten; Hjort, Jakob; Lassen, Jens Flensted; Petersen, Frants; Jensen, Jan Skov; Bäck, Caroline; Jensen, Lisette Okkels; Ravkilde, Jan; Bøtker, Hans Erik; Terkelsen, Christian Juhl.

I: European Heart Journal, Bind 38, Nr. 21, 01.06.2017, s. 1645-1652.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Tranberg, T, Lippert, FK, Christensen, EF, Stengaard, C, Hjort, J, Lassen, JF, Petersen, F, Jensen, JS, Bäck, C, Jensen, LO, Ravkilde, J, Bøtker, HE & Terkelsen, CJ 2017, 'Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study', European Heart Journal, bind 38, nr. 21, s. 1645-1652. https://doi.org/10.1093/eurheartj/ehx104

APA

Tranberg, T., Lippert, F. K., Christensen, E. F., Stengaard, C., Hjort, J., Lassen, J. F., Petersen, F., Jensen, J. S., Bäck, C., Jensen, L. O., Ravkilde, J., Bøtker, H. E., & Terkelsen, C. J. (2017). Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study. European Heart Journal, 38(21), 1645-1652. https://doi.org/10.1093/eurheartj/ehx104

Vancouver

Tranberg T, Lippert FK, Christensen EF, Stengaard C, Hjort J, Lassen JF o.a. Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study. European Heart Journal. 2017 jun 1;38(21):1645-1652. https://doi.org/10.1093/eurheartj/ehx104

Author

Tranberg, Tinne ; Lippert, Freddy K ; Christensen, Erika Frischknecht ; Stengaard, Carsten ; Hjort, Jakob ; Lassen, Jens Flensted ; Petersen, Frants ; Jensen, Jan Skov ; Bäck, Caroline ; Jensen, Lisette Okkels ; Ravkilde, Jan ; Bøtker, Hans Erik ; Terkelsen, Christian Juhl. / Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest : a nationwide study. I: European Heart Journal. 2017 ; Bind 38, Nr. 21. s. 1645-1652.

Bibtex

@article{6c263a673df34358a5e02cdd0f942f69,
title = "Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study",
abstract = "Aims: To evaluate whether the distance from the site of event to an invasive heart centre, acute coronary angiography (CAG)/percutaneous coronary intervention (PCI) and hospital-level of care (invasive heart centre vs. local hospital) is associated with survival in out-of-hospital cardiac arrest (OHCA) patients.Methods and results: Nationwide historical follow-up study of 41 186 unselected OHCA patients, in whom resuscitation was attempted between 2001 and 2013, identified through the Danish Cardiac Arrest Registry. We observed an increase in the proportion of patients receiving bystander CPR (18% in 2001, 60% in 2013, P < 0.001), achieving return of spontaneous circulation (ROSC) (10% in 2001, 29% in 2013, P < 0.001) and being admitted directly to an invasive centre (26% in 2001, 45% in 2013, P < 0.001). Simultaneously, 30-day survival rose from 5% in 2001 to 12% in 2013, P < 0.001. Among patients achieving ROSC, a larger proportion underwent acute CAG/PCI (5% in 2001, 27% in 2013, P < 0.001). The proportion of patients undergoing acute CAG/PCI annually in each region was defined as the CAG/PCI index. The following variables were associated with lower mortality in multivariable analyses: direct admission to invasive heart centre (HR 0.91, 95% CI: 0.89-0.93), CAG/PCI index (HR 0.33, 95% CI: 0.25-0.45), population density above 2000 per square kilometre (HR 0.94, 95% CI: 0.89-0.98), bystander CPR (HR 0.97, 95% CI: 0.95-0.99) and witnessed OHCA (HR 0.87, 95% CI: 0.85-0.89), whereas distance to the nearest invasive centre was not associated with survival.Conclusion: Admission to an invasive heart centre and regional performance of acute CAG/PCI were associated with improved survival in OHCA patients, whereas distance to the invasive centre was not. These results support a centralized strategy for immediate post-resuscitation care in OHCA patients.",
keywords = "Journal Article",
author = "Tinne Tranberg and Lippert, {Freddy K} and Christensen, {Erika Frischknecht} and Carsten Stengaard and Jakob Hjort and Lassen, {Jens Flensted} and Frants Petersen and Jensen, {Jan Skov} and Caroline B{\"a}ck and Jensen, {Lisette Okkels} and Jan Ravkilde and B{\o}tker, {Hans Erik} and Terkelsen, {Christian Juhl}",
year = "2017",
month = jun,
day = "1",
doi = "10.1093/eurheartj/ehx104",
language = "English",
volume = "38",
pages = "1645--1652",
journal = "European Heart Journal",
issn = "0195-668X",
publisher = "Oxford University Press",
number = "21",

}

RIS

TY - JOUR

T1 - Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest

T2 - a nationwide study

AU - Tranberg, Tinne

AU - Lippert, Freddy K

AU - Christensen, Erika Frischknecht

AU - Stengaard, Carsten

AU - Hjort, Jakob

AU - Lassen, Jens Flensted

AU - Petersen, Frants

AU - Jensen, Jan Skov

AU - Bäck, Caroline

AU - Jensen, Lisette Okkels

AU - Ravkilde, Jan

AU - Bøtker, Hans Erik

AU - Terkelsen, Christian Juhl

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Aims: To evaluate whether the distance from the site of event to an invasive heart centre, acute coronary angiography (CAG)/percutaneous coronary intervention (PCI) and hospital-level of care (invasive heart centre vs. local hospital) is associated with survival in out-of-hospital cardiac arrest (OHCA) patients.Methods and results: Nationwide historical follow-up study of 41 186 unselected OHCA patients, in whom resuscitation was attempted between 2001 and 2013, identified through the Danish Cardiac Arrest Registry. We observed an increase in the proportion of patients receiving bystander CPR (18% in 2001, 60% in 2013, P < 0.001), achieving return of spontaneous circulation (ROSC) (10% in 2001, 29% in 2013, P < 0.001) and being admitted directly to an invasive centre (26% in 2001, 45% in 2013, P < 0.001). Simultaneously, 30-day survival rose from 5% in 2001 to 12% in 2013, P < 0.001. Among patients achieving ROSC, a larger proportion underwent acute CAG/PCI (5% in 2001, 27% in 2013, P < 0.001). The proportion of patients undergoing acute CAG/PCI annually in each region was defined as the CAG/PCI index. The following variables were associated with lower mortality in multivariable analyses: direct admission to invasive heart centre (HR 0.91, 95% CI: 0.89-0.93), CAG/PCI index (HR 0.33, 95% CI: 0.25-0.45), population density above 2000 per square kilometre (HR 0.94, 95% CI: 0.89-0.98), bystander CPR (HR 0.97, 95% CI: 0.95-0.99) and witnessed OHCA (HR 0.87, 95% CI: 0.85-0.89), whereas distance to the nearest invasive centre was not associated with survival.Conclusion: Admission to an invasive heart centre and regional performance of acute CAG/PCI were associated with improved survival in OHCA patients, whereas distance to the invasive centre was not. These results support a centralized strategy for immediate post-resuscitation care in OHCA patients.

AB - Aims: To evaluate whether the distance from the site of event to an invasive heart centre, acute coronary angiography (CAG)/percutaneous coronary intervention (PCI) and hospital-level of care (invasive heart centre vs. local hospital) is associated with survival in out-of-hospital cardiac arrest (OHCA) patients.Methods and results: Nationwide historical follow-up study of 41 186 unselected OHCA patients, in whom resuscitation was attempted between 2001 and 2013, identified through the Danish Cardiac Arrest Registry. We observed an increase in the proportion of patients receiving bystander CPR (18% in 2001, 60% in 2013, P < 0.001), achieving return of spontaneous circulation (ROSC) (10% in 2001, 29% in 2013, P < 0.001) and being admitted directly to an invasive centre (26% in 2001, 45% in 2013, P < 0.001). Simultaneously, 30-day survival rose from 5% in 2001 to 12% in 2013, P < 0.001. Among patients achieving ROSC, a larger proportion underwent acute CAG/PCI (5% in 2001, 27% in 2013, P < 0.001). The proportion of patients undergoing acute CAG/PCI annually in each region was defined as the CAG/PCI index. The following variables were associated with lower mortality in multivariable analyses: direct admission to invasive heart centre (HR 0.91, 95% CI: 0.89-0.93), CAG/PCI index (HR 0.33, 95% CI: 0.25-0.45), population density above 2000 per square kilometre (HR 0.94, 95% CI: 0.89-0.98), bystander CPR (HR 0.97, 95% CI: 0.95-0.99) and witnessed OHCA (HR 0.87, 95% CI: 0.85-0.89), whereas distance to the nearest invasive centre was not associated with survival.Conclusion: Admission to an invasive heart centre and regional performance of acute CAG/PCI were associated with improved survival in OHCA patients, whereas distance to the invasive centre was not. These results support a centralized strategy for immediate post-resuscitation care in OHCA patients.

KW - Journal Article

U2 - 10.1093/eurheartj/ehx104

DO - 10.1093/eurheartj/ehx104

M3 - Journal article

C2 - 28369362

VL - 38

SP - 1645

EP - 1652

JO - European Heart Journal

JF - European Heart Journal

SN - 0195-668X

IS - 21

ER -

ID: 180548946