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Effect of endurance training on ammonia and amino acid metabolism in humans

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Few studies examine ammonia and amino acid metabolism in response to endurance training Trained humans generally experience less increase in plasma ammonia during either prolonged or intense exercise. This is probably a reflection of reduced ammonia production and release from the active muscle; it could be a reflection of decreased AMP deaminase activity, decreased glutamate dehydrogenase activity, and/or increased alanine and glutamine formation. Little is known regarding the associated enzyme systems in humans, but in experiments with animal models, aerobic training decreases AMP deaminase and increases the enzymes of amino acid transamination and oxidation.

OriginalsprogEngelsk
TidsskriftMedicine and Science in Sports and Exercise
Vol/bind29
Udgave nummer5
Sider (fra-til)646-653
Antal sider8
ISSN0195-9131
DOI
StatusUdgivet - 1997

ID: 254666293