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Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania

Publikation: KonferencebidragKonferenceabstrakt til konferenceForskningfagfællebedømt

Standard

Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania. / Braae, Uffe Christian; Magnussen, Pascal; Ndawi, Benedict; Wendy, Harrison; Lekule, Faustin; Johansen, Maria Vang.

2015. Abstract fra 1st CYSTINET International Conference, Belgrade, Serbien.

Publikation: KonferencebidragKonferenceabstrakt til konferenceForskningfagfællebedømt

Harvard

Braae, UC, Magnussen, P, Ndawi, B, Wendy, H, Lekule, F & Johansen, MV 2015, 'Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania', 1st CYSTINET International Conference, Belgrade, Serbien, 03/11/2015 - 04/11/2015.

APA

Braae, U. C., Magnussen, P., Ndawi, B., Wendy, H., Lekule, F., & Johansen, M. V. (2015). Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania. Abstract fra 1st CYSTINET International Conference, Belgrade, Serbien.

Vancouver

Braae UC, Magnussen P, Ndawi B, Wendy H, Lekule F, Johansen MV. Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania. 2015. Abstract fra 1st CYSTINET International Conference, Belgrade, Serbien.

Author

Braae, Uffe Christian ; Magnussen, Pascal ; Ndawi, Benedict ; Wendy, Harrison ; Lekule, Faustin ; Johansen, Maria Vang. / Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania. Abstract fra 1st CYSTINET International Conference, Belgrade, Serbien.

Bibtex

@conference{bbb965e9bb254767846b3d5a7d06a561,
title = "Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania",
abstract = "This study evaluated the effect of mass drug administration (MDA) with praziquantel administered to school-aged children (SAC) combined with ‘track and treat’ of taeniosis cases on the prevalence of taeniosis. The study was conducted in 14 villages in Mbozi and Mbeya district, Tanzania. SAC received MDA with praziquantel in 2012 (both districts) and in 2013 (Mbozi only). Three cross-sectional population-based surveys were performed in 2012 (R0), 2013 (R1), and 2014 (R2). In each survey approximately 3,000 participants of all ages were tested using copro-antigen-ELISA. The prevalence of taeniosis was significantly higher (p=0.007) in Mbozi (3.0{\%}) at R0 compared to Mbeya (1.5{\%}). Twelve months after MDA in both districts (R1), the prevalence had dropped significantly in both Mbozi (2.0{\%}, p=0.024) and in Mbeya (0.3{\%}, p=0.004), but the significant difference between the districts persisted (p<0.001). Ten months after the second round of MDA in Mbozi (R2), the prevalence had dropped significantly again in Mbozi (0.8{\%}, p<0.001), but had slightly increased in Mbeya (0.5{\%}, p=0.051), with no difference between the two (p=0.51). Among SAC in Mbozi, infection significantly decreased at R1 (p=0.004, OR 0.12 CI: 0.02-0.41) and R2 (p=0.001, OR 0.24, CI: 0.09-0.53) when comparing to R0. In Mbeya infection decreased at R1 (p=0.013, OR 0.14, CI: 0.02-0.55), but no difference was found for R2 (p=0. 089), compared to R0 among SAC. This study showed that school-based MDA with praziquantel in combination with ‘track and treat’ of taeniosis cases reduced the prevalence of taeniosis, and that annual MDA was better than biennially MDA.",
author = "Braae, {Uffe Christian} and Pascal Magnussen and Benedict Ndawi and Harrison Wendy and Faustin Lekule and Johansen, {Maria Vang}",
year = "2015",
month = "11",
day = "3",
language = "English",
note = "1st CYSTINET International Conference ; Conference date: 03-11-2015 Through 04-11-2015",

}

RIS

TY - ABST

T1 - Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania

AU - Braae, Uffe Christian

AU - Magnussen, Pascal

AU - Ndawi, Benedict

AU - Wendy, Harrison

AU - Lekule, Faustin

AU - Johansen, Maria Vang

PY - 2015/11/3

Y1 - 2015/11/3

N2 - This study evaluated the effect of mass drug administration (MDA) with praziquantel administered to school-aged children (SAC) combined with ‘track and treat’ of taeniosis cases on the prevalence of taeniosis. The study was conducted in 14 villages in Mbozi and Mbeya district, Tanzania. SAC received MDA with praziquantel in 2012 (both districts) and in 2013 (Mbozi only). Three cross-sectional population-based surveys were performed in 2012 (R0), 2013 (R1), and 2014 (R2). In each survey approximately 3,000 participants of all ages were tested using copro-antigen-ELISA. The prevalence of taeniosis was significantly higher (p=0.007) in Mbozi (3.0%) at R0 compared to Mbeya (1.5%). Twelve months after MDA in both districts (R1), the prevalence had dropped significantly in both Mbozi (2.0%, p=0.024) and in Mbeya (0.3%, p=0.004), but the significant difference between the districts persisted (p<0.001). Ten months after the second round of MDA in Mbozi (R2), the prevalence had dropped significantly again in Mbozi (0.8%, p<0.001), but had slightly increased in Mbeya (0.5%, p=0.051), with no difference between the two (p=0.51). Among SAC in Mbozi, infection significantly decreased at R1 (p=0.004, OR 0.12 CI: 0.02-0.41) and R2 (p=0.001, OR 0.24, CI: 0.09-0.53) when comparing to R0. In Mbeya infection decreased at R1 (p=0.013, OR 0.14, CI: 0.02-0.55), but no difference was found for R2 (p=0. 089), compared to R0 among SAC. This study showed that school-based MDA with praziquantel in combination with ‘track and treat’ of taeniosis cases reduced the prevalence of taeniosis, and that annual MDA was better than biennially MDA.

AB - This study evaluated the effect of mass drug administration (MDA) with praziquantel administered to school-aged children (SAC) combined with ‘track and treat’ of taeniosis cases on the prevalence of taeniosis. The study was conducted in 14 villages in Mbozi and Mbeya district, Tanzania. SAC received MDA with praziquantel in 2012 (both districts) and in 2013 (Mbozi only). Three cross-sectional population-based surveys were performed in 2012 (R0), 2013 (R1), and 2014 (R2). In each survey approximately 3,000 participants of all ages were tested using copro-antigen-ELISA. The prevalence of taeniosis was significantly higher (p=0.007) in Mbozi (3.0%) at R0 compared to Mbeya (1.5%). Twelve months after MDA in both districts (R1), the prevalence had dropped significantly in both Mbozi (2.0%, p=0.024) and in Mbeya (0.3%, p=0.004), but the significant difference between the districts persisted (p<0.001). Ten months after the second round of MDA in Mbozi (R2), the prevalence had dropped significantly again in Mbozi (0.8%, p<0.001), but had slightly increased in Mbeya (0.5%, p=0.051), with no difference between the two (p=0.51). Among SAC in Mbozi, infection significantly decreased at R1 (p=0.004, OR 0.12 CI: 0.02-0.41) and R2 (p=0.001, OR 0.24, CI: 0.09-0.53) when comparing to R0. In Mbeya infection decreased at R1 (p=0.013, OR 0.14, CI: 0.02-0.55), but no difference was found for R2 (p=0. 089), compared to R0 among SAC. This study showed that school-based MDA with praziquantel in combination with ‘track and treat’ of taeniosis cases reduced the prevalence of taeniosis, and that annual MDA was better than biennially MDA.

M3 - Conference abstract for conference

T2 - 1st CYSTINET International Conference

Y2 - 3 November 2015 through 4 November 2015

ER -

ID: 147497064