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Endocrine therapy of human breast cancer grown in nude mice

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Standard

Endocrine therapy of human breast cancer grown in nude mice. / Brünner, N; Osborne, C K; Spang-Thomsen, M.

I: Breast Cancer Research and Treatment, Bind 10, Nr. 3, 1987, s. 229-42.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Brünner, N, Osborne, CK & Spang-Thomsen, M 1987, 'Endocrine therapy of human breast cancer grown in nude mice', Breast Cancer Research and Treatment, bind 10, nr. 3, s. 229-42.

APA

Brünner, N., Osborne, C. K., & Spang-Thomsen, M. (1987). Endocrine therapy of human breast cancer grown in nude mice. Breast Cancer Research and Treatment, 10(3), 229-42.

Vancouver

Brünner N, Osborne CK, Spang-Thomsen M. Endocrine therapy of human breast cancer grown in nude mice. Breast Cancer Research and Treatment. 1987;10(3):229-42.

Author

Brünner, N ; Osborne, C K ; Spang-Thomsen, M. / Endocrine therapy of human breast cancer grown in nude mice. I: Breast Cancer Research and Treatment. 1987 ; Bind 10, Nr. 3. s. 229-42.

Bibtex

@article{6fe194d0654f11de8bc9000ea68e967b,
title = "Endocrine therapy of human breast cancer grown in nude mice",
abstract = "Although there have been extensive studies of rodent breast tumor models, and of human breast cancer cell lines in culture, there is still need for a human tumor model which can be manipulated experimentally but also provides a valid expression of the tumor cells in a host environment. Athymic nude mice bearing transplanted human breast tumors have been proposed as such a model. This review therefore discusses the use of the athymic nude mouse model of the study of human breast cancer biology, and focuses on four subjects: 1. biological characteristics of heterotransplanted breast tumors; 2. endocrinology and pharmacology of hormonal agents in the nude mouse; 3. endocrine sensitivity of heterotransplanted tumors; and 4. applicability and limitations of this model for the study of human breast cancer.",
author = "N Br{\"u}nner and Osborne, {C K} and M Spang-Thomsen",
note = "Keywords: Animals; Breast Neoplasms; Disease Models, Animal; Female; Flow Cytometry; Hormones; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Transplantation, Heterologous",
year = "1987",
language = "English",
volume = "10",
pages = "229--42",
journal = "Breast Cancer Research and Treatment",
issn = "0167-6806",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Endocrine therapy of human breast cancer grown in nude mice

AU - Brünner, N

AU - Osborne, C K

AU - Spang-Thomsen, M

N1 - Keywords: Animals; Breast Neoplasms; Disease Models, Animal; Female; Flow Cytometry; Hormones; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Transplantation, Heterologous

PY - 1987

Y1 - 1987

N2 - Although there have been extensive studies of rodent breast tumor models, and of human breast cancer cell lines in culture, there is still need for a human tumor model which can be manipulated experimentally but also provides a valid expression of the tumor cells in a host environment. Athymic nude mice bearing transplanted human breast tumors have been proposed as such a model. This review therefore discusses the use of the athymic nude mouse model of the study of human breast cancer biology, and focuses on four subjects: 1. biological characteristics of heterotransplanted breast tumors; 2. endocrinology and pharmacology of hormonal agents in the nude mouse; 3. endocrine sensitivity of heterotransplanted tumors; and 4. applicability and limitations of this model for the study of human breast cancer.

AB - Although there have been extensive studies of rodent breast tumor models, and of human breast cancer cell lines in culture, there is still need for a human tumor model which can be manipulated experimentally but also provides a valid expression of the tumor cells in a host environment. Athymic nude mice bearing transplanted human breast tumors have been proposed as such a model. This review therefore discusses the use of the athymic nude mouse model of the study of human breast cancer biology, and focuses on four subjects: 1. biological characteristics of heterotransplanted breast tumors; 2. endocrinology and pharmacology of hormonal agents in the nude mouse; 3. endocrine sensitivity of heterotransplanted tumors; and 4. applicability and limitations of this model for the study of human breast cancer.

M3 - Journal article

C2 - 3328985

VL - 10

SP - 229

EP - 242

JO - Breast Cancer Research and Treatment

JF - Breast Cancer Research and Treatment

SN - 0167-6806

IS - 3

ER -

ID: 12871033