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"Every drug goes to treat its own disease…" - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania

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"Every drug goes to treat its own disease…" - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania. / Mangesho, Peter E; Reynolds, Joanna; Lemnge, Martha; Vestergaard, Lasse S; Chandler, Clare I R.

I: Malaria Journal, Bind 13, 491, 2014, s. 1-9.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Mangesho, PE, Reynolds, J, Lemnge, M, Vestergaard, LS & Chandler, CIR 2014, '"Every drug goes to treat its own disease…" - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania', Malaria Journal, bind 13, 491, s. 1-9. https://doi.org/10.1186/1475-2875-13-491

APA

Mangesho, P. E., Reynolds, J., Lemnge, M., Vestergaard, L. S., & Chandler, C. I. R. (2014). "Every drug goes to treat its own disease…" - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania. Malaria Journal, 13, 1-9. [491]. https://doi.org/10.1186/1475-2875-13-491

Vancouver

Mangesho PE, Reynolds J, Lemnge M, Vestergaard LS, Chandler CIR. "Every drug goes to treat its own disease…" - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania. Malaria Journal. 2014;13:1-9. 491. https://doi.org/10.1186/1475-2875-13-491

Author

Mangesho, Peter E ; Reynolds, Joanna ; Lemnge, Martha ; Vestergaard, Lasse S ; Chandler, Clare I R. / "Every drug goes to treat its own disease…" - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania. I: Malaria Journal. 2014 ; Bind 13. s. 1-9.

Bibtex

@article{2b1cbe13fb8a4490b7b98c8a13642dac,
title = "{"}Every drug goes to treat its own disease…{"} - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania",
abstract = "BACKGROUND: Little is known about how people living with human immunodeficiency virus (HIV) experience malaria and the concomitant use of anti-malarial treatments with anti-retrovirals (ARVs). An understanding of how patients make sense of these experiences is important to consider in planning and supporting the clinical management and treatment for co-infected individuals.METHODS: A qualitative study was conducted in Tanzania alongside a clinical trial of concomitant treatment for HIV and malaria co-infection. Focus group discussions were held with people receiving treatment for HIV and/or malaria, and in-depth interviews with health workers responsible for HIV care and members of the clinical trial team. Data were analysed inductively to identify themes and develop theoretical narratives.RESULTS: Results suggest that people living with HIV perceived malaria to be more harmful to them due to their compromised immune status but saw the disease as unavoidable. For those enrolled in the clinical controlled study, taking anti-malarials together with ARVs was largely seen as unproblematic, with health workers' advice and endorsement of concomitant drug taking influential in reported adherence. However, perceptions of drug strength appeared to compel some people not enrolled in the clinical study to take the drugs at separate times to avoid anticipated harm to the body.CONCLUSIONS: Management of HIV and malaria concurrently often requires individuals to cross the domains of different disease programmes. In the context of a trial concerned with both diseases, patients experienced the support of clinicians in guiding and reassuring them about when and how to take drugs concomitantly. This points towards the need to continue to strive for integrated care for patients with HIV.",
keywords = "Anti-HIV Agents, Antimalarials, Coinfection, Drug Therapy, Combination, Female, Focus Groups, HIV Infections, Health Knowledge, Attitudes, Practice, Health Personnel, Humans, Malaria, Male, Tanzania",
author = "Mangesho, {Peter E} and Joanna Reynolds and Martha Lemnge and Vestergaard, {Lasse S} and Chandler, {Clare I R}",
year = "2014",
doi = "10.1186/1475-2875-13-491",
language = "English",
volume = "13",
pages = "1--9",
journal = "Malaria Journal",
issn = "1475-2875",
publisher = "BioMed Central",

}

RIS

TY - JOUR

T1 - "Every drug goes to treat its own disease…" - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania

AU - Mangesho, Peter E

AU - Reynolds, Joanna

AU - Lemnge, Martha

AU - Vestergaard, Lasse S

AU - Chandler, Clare I R

PY - 2014

Y1 - 2014

N2 - BACKGROUND: Little is known about how people living with human immunodeficiency virus (HIV) experience malaria and the concomitant use of anti-malarial treatments with anti-retrovirals (ARVs). An understanding of how patients make sense of these experiences is important to consider in planning and supporting the clinical management and treatment for co-infected individuals.METHODS: A qualitative study was conducted in Tanzania alongside a clinical trial of concomitant treatment for HIV and malaria co-infection. Focus group discussions were held with people receiving treatment for HIV and/or malaria, and in-depth interviews with health workers responsible for HIV care and members of the clinical trial team. Data were analysed inductively to identify themes and develop theoretical narratives.RESULTS: Results suggest that people living with HIV perceived malaria to be more harmful to them due to their compromised immune status but saw the disease as unavoidable. For those enrolled in the clinical controlled study, taking anti-malarials together with ARVs was largely seen as unproblematic, with health workers' advice and endorsement of concomitant drug taking influential in reported adherence. However, perceptions of drug strength appeared to compel some people not enrolled in the clinical study to take the drugs at separate times to avoid anticipated harm to the body.CONCLUSIONS: Management of HIV and malaria concurrently often requires individuals to cross the domains of different disease programmes. In the context of a trial concerned with both diseases, patients experienced the support of clinicians in guiding and reassuring them about when and how to take drugs concomitantly. This points towards the need to continue to strive for integrated care for patients with HIV.

AB - BACKGROUND: Little is known about how people living with human immunodeficiency virus (HIV) experience malaria and the concomitant use of anti-malarial treatments with anti-retrovirals (ARVs). An understanding of how patients make sense of these experiences is important to consider in planning and supporting the clinical management and treatment for co-infected individuals.METHODS: A qualitative study was conducted in Tanzania alongside a clinical trial of concomitant treatment for HIV and malaria co-infection. Focus group discussions were held with people receiving treatment for HIV and/or malaria, and in-depth interviews with health workers responsible for HIV care and members of the clinical trial team. Data were analysed inductively to identify themes and develop theoretical narratives.RESULTS: Results suggest that people living with HIV perceived malaria to be more harmful to them due to their compromised immune status but saw the disease as unavoidable. For those enrolled in the clinical controlled study, taking anti-malarials together with ARVs was largely seen as unproblematic, with health workers' advice and endorsement of concomitant drug taking influential in reported adherence. However, perceptions of drug strength appeared to compel some people not enrolled in the clinical study to take the drugs at separate times to avoid anticipated harm to the body.CONCLUSIONS: Management of HIV and malaria concurrently often requires individuals to cross the domains of different disease programmes. In the context of a trial concerned with both diseases, patients experienced the support of clinicians in guiding and reassuring them about when and how to take drugs concomitantly. This points towards the need to continue to strive for integrated care for patients with HIV.

KW - Anti-HIV Agents

KW - Antimalarials

KW - Coinfection

KW - Drug Therapy, Combination

KW - Female

KW - Focus Groups

KW - HIV Infections

KW - Health Knowledge, Attitudes, Practice

KW - Health Personnel

KW - Humans

KW - Malaria

KW - Male

KW - Tanzania

U2 - 10.1186/1475-2875-13-491

DO - 10.1186/1475-2875-13-491

M3 - Journal article

C2 - 25495956

VL - 13

SP - 1

EP - 9

JO - Malaria Journal

JF - Malaria Journal

SN - 1475-2875

M1 - 491

ER -

ID: 151549688