Forskning ved Københavns Universitet - Københavns Universitet

Forside

Failure of total hip implants: metals and metal release in 52 cases

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Failure of total hip implants : metals and metal release in 52 cases. / Jakobsen, Stig S; Lidén, Carola; Søballe, Kjeld; Johansen, Jeanne D; Menné, Torkil; Lundgren, Lennart; Bregnbak, David; Møller, Per; Jellesen, Morten S; Thyssen, Jacob P.

I: Contact Dermatitis, Bind 71, Nr. 6, 12.2014, s. 319–325.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Jakobsen, SS, Lidén, C, Søballe, K, Johansen, JD, Menné, T, Lundgren, L, Bregnbak, D, Møller, P, Jellesen, MS & Thyssen, JP 2014, 'Failure of total hip implants: metals and metal release in 52 cases', Contact Dermatitis, bind 71, nr. 6, s. 319–325. https://doi.org/10.1111/cod.12275

APA

Jakobsen, S. S., Lidén, C., Søballe, K., Johansen, J. D., Menné, T., Lundgren, L., Bregnbak, D., Møller, P., Jellesen, M. S., & Thyssen, J. P. (2014). Failure of total hip implants: metals and metal release in 52 cases. Contact Dermatitis, 71(6), 319–325. https://doi.org/10.1111/cod.12275

Vancouver

Jakobsen SS, Lidén C, Søballe K, Johansen JD, Menné T, Lundgren L o.a. Failure of total hip implants: metals and metal release in 52 cases. Contact Dermatitis. 2014 dec;71(6):319–325. https://doi.org/10.1111/cod.12275

Author

Jakobsen, Stig S ; Lidén, Carola ; Søballe, Kjeld ; Johansen, Jeanne D ; Menné, Torkil ; Lundgren, Lennart ; Bregnbak, David ; Møller, Per ; Jellesen, Morten S ; Thyssen, Jacob P. / Failure of total hip implants : metals and metal release in 52 cases. I: Contact Dermatitis. 2014 ; Bind 71, Nr. 6. s. 319–325.

Bibtex

@article{c506378b2f244df7947cf6704d611da6,
title = "Failure of total hip implants: metals and metal release in 52 cases",
abstract = "BACKGROUND: The pathogenesis of total joint replacement failure is multifactorial. One hypothesis suggests that corrosion and wear of alloys result in metal ion release, which may then cause sensitization and even implant failure, owing to the acquired immune reactivity.OBJECTIVES: To assess cobalt, nickel and chromium(VI) release from, and the metal composition of, failed metal-on-ethylene total hip replacements.MATERIALS/METHODS: Implant components from 52 revision cases were evaluated with spot tests for free nickel, cobalt, and chromium (VI) ions. Implant composition was determined with X-ray fluorescence spectroscopy, and information on the reason for revision and complications in relation to surgery was collected from the medical charts when possible (72%). For 10 implants, corrosion was further characterized with scanning electron microscopy.RESULTS: We detected cobalt release from three of 38 removed femoral heads and from one of 24 femoral stems. Nickel release was detected from one of 24 femoral stems. No chromium(VI) release was detected.CONCLUSIONS: We found that cobalt and nickel were released from some failed total hip arthroplasties, and corrosion was frequently observed. Metal ions and particles corroded from metal-on-polyethylene may play a role in the complex aetiopathology of implant failure.",
author = "Jakobsen, {Stig S} and Carola Lid{\'e}n and Kjeld S{\o}balle and Johansen, {Jeanne D} and Torkil Menn{\'e} and Lennart Lundgren and David Bregnbak and Per M{\o}ller and Jellesen, {Morten S} and Thyssen, {Jacob P}",
note = "{\textcopyright} 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2014",
month = dec,
doi = "10.1111/cod.12275",
language = "English",
volume = "71",
pages = "319–325",
journal = "Contact Dermatitis",
issn = "0105-1873",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Failure of total hip implants

T2 - metals and metal release in 52 cases

AU - Jakobsen, Stig S

AU - Lidén, Carola

AU - Søballe, Kjeld

AU - Johansen, Jeanne D

AU - Menné, Torkil

AU - Lundgren, Lennart

AU - Bregnbak, David

AU - Møller, Per

AU - Jellesen, Morten S

AU - Thyssen, Jacob P

N1 - © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2014/12

Y1 - 2014/12

N2 - BACKGROUND: The pathogenesis of total joint replacement failure is multifactorial. One hypothesis suggests that corrosion and wear of alloys result in metal ion release, which may then cause sensitization and even implant failure, owing to the acquired immune reactivity.OBJECTIVES: To assess cobalt, nickel and chromium(VI) release from, and the metal composition of, failed metal-on-ethylene total hip replacements.MATERIALS/METHODS: Implant components from 52 revision cases were evaluated with spot tests for free nickel, cobalt, and chromium (VI) ions. Implant composition was determined with X-ray fluorescence spectroscopy, and information on the reason for revision and complications in relation to surgery was collected from the medical charts when possible (72%). For 10 implants, corrosion was further characterized with scanning electron microscopy.RESULTS: We detected cobalt release from three of 38 removed femoral heads and from one of 24 femoral stems. Nickel release was detected from one of 24 femoral stems. No chromium(VI) release was detected.CONCLUSIONS: We found that cobalt and nickel were released from some failed total hip arthroplasties, and corrosion was frequently observed. Metal ions and particles corroded from metal-on-polyethylene may play a role in the complex aetiopathology of implant failure.

AB - BACKGROUND: The pathogenesis of total joint replacement failure is multifactorial. One hypothesis suggests that corrosion and wear of alloys result in metal ion release, which may then cause sensitization and even implant failure, owing to the acquired immune reactivity.OBJECTIVES: To assess cobalt, nickel and chromium(VI) release from, and the metal composition of, failed metal-on-ethylene total hip replacements.MATERIALS/METHODS: Implant components from 52 revision cases were evaluated with spot tests for free nickel, cobalt, and chromium (VI) ions. Implant composition was determined with X-ray fluorescence spectroscopy, and information on the reason for revision and complications in relation to surgery was collected from the medical charts when possible (72%). For 10 implants, corrosion was further characterized with scanning electron microscopy.RESULTS: We detected cobalt release from three of 38 removed femoral heads and from one of 24 femoral stems. Nickel release was detected from one of 24 femoral stems. No chromium(VI) release was detected.CONCLUSIONS: We found that cobalt and nickel were released from some failed total hip arthroplasties, and corrosion was frequently observed. Metal ions and particles corroded from metal-on-polyethylene may play a role in the complex aetiopathology of implant failure.

U2 - 10.1111/cod.12275

DO - 10.1111/cod.12275

M3 - Journal article

C2 - 25041132

VL - 71

SP - 319

EP - 325

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 6

ER -

ID: 137962304