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Fokker-Planck and Fortet equation-based parameter estimation for a leaky integrate-and-fire model with sinusoidal and stochastic forcing

Publikation: Bidrag til tidsskriftTidsskriftartikel

Analysis of sinusoidal noisy leaky integrate-and-fire models and comparison with experimental data are important to understand the neural code and neural synchronization and rhythms. In this paper, we propose two methods to estimate input parameters using interspike interval data only. One is based on numerical solutions of the Fokker–Planck equation, and the other is based on an integral equation, which is fulfilled by the interspike interval probability density. This generalizes previous methods tailored to stationary data to the case of time-dependent input. The main contribution is a binning method to circumvent the problems of nonstationarity, and an easy-to-implement initializer for the numerical procedures. The methods are compared on simulated data
OriginalsprogEngelsk
Artikelnummer4
TidsskriftJournal of Mathematical Neuroscience
Vol/bind4
Udgave nummer4
Antal sider30
ISSN2190-8567
DOI
StatusUdgivet - 2014

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