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Forekomsten af komplementdefekter ved meningokoksygdom: Hvem skal undersøges?

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

Congenital complement deficiency states occur very rarely. These deficiencies are associated with a high risk of meningococcal disease (MD). We suggest that the following groups of individuals with MD are examined for complement deficiencies: 1. Individuals belonging to families, in which more than one case of MD has occurred with an interval exceeding one month. 2. Individuals infected with the low-virulent meningococcal serogroups W-135, 29E, X, Y, Z. 3. Individuals with recurrent MD. Since properdin deficiency probably is the most common deficiency associated with MD it is important that the screening includes the alternative complement pathway.

OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind153
Udgave nummer16
Sider (fra-til)1113-1116
Antal sider4
ISSN0041-5782
StatusUdgivet - 1 jan. 1991

ID: 224709483