Forskning ved Københavns Universitet - Københavns Universitet


Fructose-2,6-bisphosphate: a traffic signal in plant metabolism

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Fructose-2,6-bisphosphate (Fru-2,6-P2) regulates key reactions of the primary carbohydrate metabolism in all eukaryotes. In plants, Fru-2,6-P2 coordinates the photosynthetic carbon flux into sucrose and starch biosynthesis. The use of transgenic plants has allowed the regulatory models to be tested by modifying the Fru-2,6-P2 levels and the enzymes regulated by Fru-2,6-P2. Genes for the bifunctional plant enzyme that synthesizes and degrades Fru-2,6-P2 have been isolated and molecular characterization has provided new insight into structure and molecular regulation of the enzyme. Advances in Fru-2,6-P2 physiology and molecular biology are discussed. These advances have not only enlightened in vivo operation of Fru-2,6-P2 but also revealed that the Fru-2,6-P2 regulatory system is highly complex and interacts with other regulatory mechanisms.
TidsskriftTrends in Plant Science
Udgave nummer11
Sider (fra-til)556-563
Antal sider8
StatusUdgivet - 2004

ID: 8063272