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Functions of myosin motors tailored for parasitism

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

  • Christina Mueller
  • Arnault Graindorge
  • Dominique Soldati-Favre

Myosin motors are one of the largest protein families in eukaryotes that exhibit divergent cellular functions. Their roles in protozoans, a diverse group of anciently diverged, single celled organisms with many prominent members known to be parasitic and to cause diseases in human and livestock, are largely unknown. In the recent years many different approaches, among them whole genome sequencing, phylogenetic analyses and functional studies have increased our understanding on the distribution, protein architecture and function of unconventional myosin motors in protozoan parasites. In Apicomplexa, myosins turn out to be highly specialized and to exhibit unique functions tailored to accommodate the lifestyle of these parasites.

OriginalsprogEngelsk
TidsskriftCurrent Opinion in Microbiology
Vol/bind40
Sider (fra-til)113-122
Antal sider10
ISSN1369-5274
DOI
StatusUdgivet - 1 dec. 2017

ID: 186634816