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Fusidic acid for Behçet's colitis: a novel approach to T-cell specific immunosuppressive therapy

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A 33-year-old patient suffered from recurring Beh,cet's colitis despite treatment with corticosteroids and later cyclosporin. The patient was then successfully shifted from cyclosporin, a T-cell specific immunosuppressant, to fusidic acid treatment (500 mg t.i.d.). During fusidic acid treatment, he went into complete remission, and his prednisolone dose could be reduced from 30 to 5 mg/day. The case report substantiates recent in vitro data indicating that fusidic acid has a similar effect on T-cell function as cyclosporin. It is suggested that the effect of fusidic acid in other chronic immunoinflammatory diseases should be examined.

OriginalsprogEngelsk
TidsskriftDanish Medical Bulletin (Print)
Vol/bind38
Udgave nummer3
Sider (fra-til)284
ISSN0907-8916
StatusUdgivet - jun. 1991

ID: 219531521