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HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products. / Mølgaard, Per; Johnsen, Søren; Christensen, Peter; Cornett, Claus.

I: Journal of Agricultural and Food Chemistry, Bind 51, Nr. 24, 2003, s. 6922-33.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Mølgaard, P, Johnsen, S, Christensen, P & Cornett, C 2003, 'HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products', Journal of Agricultural and Food Chemistry, bind 51, nr. 24, s. 6922-33. https://doi.org/10.1021/jf026158f

APA

Mølgaard, P., Johnsen, S., Christensen, P., & Cornett, C. (2003). HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products. Journal of Agricultural and Food Chemistry, 51(24), 6922-33. https://doi.org/10.1021/jf026158f

Vancouver

Mølgaard P, Johnsen S, Christensen P, Cornett C. HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products. Journal of Agricultural and Food Chemistry. 2003;51(24):6922-33. https://doi.org/10.1021/jf026158f

Author

Mølgaard, Per ; Johnsen, Søren ; Christensen, Peter ; Cornett, Claus. / HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products. I: Journal of Agricultural and Food Chemistry. 2003 ; Bind 51, Nr. 24. s. 6922-33.

Bibtex

@article{c062cfa0c69911dd9473000ea68e967b,
title = "HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products",
abstract = "A reversed-phase high-performance liquid chromatography (HPLC) method has been developed to determine caffeic acid derivatives, for example, cichoric acid, and alkamides in plant parts and herbal products of Echinacea purpurea. The method consists of an extraction procedure whereby the hydrophilic phenolics as well as the lipophilic alkamides are released from the samples, followed by the analytical HPLC procedure for quantitative determination of these compounds. The method is the first one validated for the determination of these two groups of compounds in the same procedure. Naringenin has been used as an internal standard, as no other flavanones are present in the extract and it does not interfere with any of the compounds under investigation. Analysis of Danish-grown plant material shows that it is possible to raise plants of a very high chemical quality in Denmark. A selection of international herbal products available on the Danish market show surprisingly variable quality, not necessarily reflecting the product information given on the labels.",
author = "Per M{\o}lgaard and S{\o}ren Johnsen and Peter Christensen and Claus Cornett",
note = "Keywords: Amides; Caffeic Acids; Chromatography, High Pressure Liquid; Denmark; Echinacea; Plant Extracts; Plant Preparations; Quality Control; Succinates",
year = "2003",
doi = "10.1021/jf026158f",
language = "English",
volume = "51",
pages = "6922--33",
journal = "Journal of Agricultural and Food Chemistry",
issn = "0021-8561",
publisher = "American Chemical Society",
number = "24",

}

RIS

TY - JOUR

T1 - HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products

AU - Mølgaard, Per

AU - Johnsen, Søren

AU - Christensen, Peter

AU - Cornett, Claus

N1 - Keywords: Amides; Caffeic Acids; Chromatography, High Pressure Liquid; Denmark; Echinacea; Plant Extracts; Plant Preparations; Quality Control; Succinates

PY - 2003

Y1 - 2003

N2 - A reversed-phase high-performance liquid chromatography (HPLC) method has been developed to determine caffeic acid derivatives, for example, cichoric acid, and alkamides in plant parts and herbal products of Echinacea purpurea. The method consists of an extraction procedure whereby the hydrophilic phenolics as well as the lipophilic alkamides are released from the samples, followed by the analytical HPLC procedure for quantitative determination of these compounds. The method is the first one validated for the determination of these two groups of compounds in the same procedure. Naringenin has been used as an internal standard, as no other flavanones are present in the extract and it does not interfere with any of the compounds under investigation. Analysis of Danish-grown plant material shows that it is possible to raise plants of a very high chemical quality in Denmark. A selection of international herbal products available on the Danish market show surprisingly variable quality, not necessarily reflecting the product information given on the labels.

AB - A reversed-phase high-performance liquid chromatography (HPLC) method has been developed to determine caffeic acid derivatives, for example, cichoric acid, and alkamides in plant parts and herbal products of Echinacea purpurea. The method consists of an extraction procedure whereby the hydrophilic phenolics as well as the lipophilic alkamides are released from the samples, followed by the analytical HPLC procedure for quantitative determination of these compounds. The method is the first one validated for the determination of these two groups of compounds in the same procedure. Naringenin has been used as an internal standard, as no other flavanones are present in the extract and it does not interfere with any of the compounds under investigation. Analysis of Danish-grown plant material shows that it is possible to raise plants of a very high chemical quality in Denmark. A selection of international herbal products available on the Danish market show surprisingly variable quality, not necessarily reflecting the product information given on the labels.

U2 - 10.1021/jf026158f

DO - 10.1021/jf026158f

M3 - Journal article

C2 - 14611148

VL - 51

SP - 6922

EP - 6933

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

SN - 0021-8561

IS - 24

ER -

ID: 9040256