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Human parallels to experimental myopia? A literature review on visual deprivation

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

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Human parallels to experimental myopia? A literature review on visual deprivation. / Fledelius, Hans C; Goldschmidt, Ernst; Haargaard, Birgitte; Jensen, Hanne.

I: Acta Ophthalmologica, Bind 92, Nr. 8, 12.2014, s. 724-729.

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

Harvard

Fledelius, HC, Goldschmidt, E, Haargaard, B & Jensen, H 2014, 'Human parallels to experimental myopia? A literature review on visual deprivation', Acta Ophthalmologica, bind 92, nr. 8, s. 724-729. https://doi.org/10.1111/aos.12412

APA

Fledelius, H. C., Goldschmidt, E., Haargaard, B., & Jensen, H. (2014). Human parallels to experimental myopia? A literature review on visual deprivation. Acta Ophthalmologica, 92(8), 724-729. https://doi.org/10.1111/aos.12412

Vancouver

Fledelius HC, Goldschmidt E, Haargaard B, Jensen H. Human parallels to experimental myopia? A literature review on visual deprivation. Acta Ophthalmologica. 2014 dec;92(8):724-729. https://doi.org/10.1111/aos.12412

Author

Fledelius, Hans C ; Goldschmidt, Ernst ; Haargaard, Birgitte ; Jensen, Hanne. / Human parallels to experimental myopia? A literature review on visual deprivation. I: Acta Ophthalmologica. 2014 ; Bind 92, Nr. 8. s. 724-729.

Bibtex

@article{00108875a22a4dafac473d80ee9d1e0c,
title = "Human parallels to experimental myopia?: A literature review on visual deprivation",
abstract = "Raviola and Wiesel's monkey eyelid suture studies of the 1970s laid the cornerstone for the experimental myopia science undertaken since then. The aim has been to clarify the basic humoral and neuronal mechanisms behind induced myopization, its eye tissue transmitters in particular. Besides acquiring new and basic knowledge, the practical object of the research is to reduce the burden of human myopia around the world. Acquisition and cost of optical correction is one issue, but associated morbidity counts more, with its global load of myopia-associated visual loss and blindness. The object of the present PubMed literature-based review is to evaluate apparent similarities between experience from disturbed imaging in experimental laboratory science and varieties within the spectrum of childhood human myopia. So far, the main impression is that macroscopical optical deprivation appears absent in the prevalent types of human myopia, nor is myopia a regular sequel where early eye pathology has led to poor imaging and optical deprivation. Optical aberrations of a higher order are a relatively new issue in myopia research, and microstructural deprivation is only marginally dealt within the survey. Links between experimental and human myopia appear mainly occasional, and with only few examples in humans where factual parallels appear credible. Clinical and epidemiological data on refraction remain important, in particular with a view to life style and environmental factors. Such knowledge may further serve as inspiration to the laboratory research, which aims at solving the basic enigmas on a tissue level.",
keywords = "Animals, Cataract, Corneal Diseases, Disease Models, Animal, Humans, Myopia, Sensory Deprivation",
author = "Fledelius, {Hans C} and Ernst Goldschmidt and Birgitte Haargaard and Hanne Jensen",
note = "{\textcopyright} 2014 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.",
year = "2014",
month = dec,
doi = "10.1111/aos.12412",
language = "English",
volume = "92",
pages = "724--729",
journal = "Acta Ophthalmologica",
issn = "1755-375X",
publisher = "Wiley-Blackwell",
number = "8",

}

RIS

TY - JOUR

T1 - Human parallels to experimental myopia?

T2 - A literature review on visual deprivation

AU - Fledelius, Hans C

AU - Goldschmidt, Ernst

AU - Haargaard, Birgitte

AU - Jensen, Hanne

N1 - © 2014 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

PY - 2014/12

Y1 - 2014/12

N2 - Raviola and Wiesel's monkey eyelid suture studies of the 1970s laid the cornerstone for the experimental myopia science undertaken since then. The aim has been to clarify the basic humoral and neuronal mechanisms behind induced myopization, its eye tissue transmitters in particular. Besides acquiring new and basic knowledge, the practical object of the research is to reduce the burden of human myopia around the world. Acquisition and cost of optical correction is one issue, but associated morbidity counts more, with its global load of myopia-associated visual loss and blindness. The object of the present PubMed literature-based review is to evaluate apparent similarities between experience from disturbed imaging in experimental laboratory science and varieties within the spectrum of childhood human myopia. So far, the main impression is that macroscopical optical deprivation appears absent in the prevalent types of human myopia, nor is myopia a regular sequel where early eye pathology has led to poor imaging and optical deprivation. Optical aberrations of a higher order are a relatively new issue in myopia research, and microstructural deprivation is only marginally dealt within the survey. Links between experimental and human myopia appear mainly occasional, and with only few examples in humans where factual parallels appear credible. Clinical and epidemiological data on refraction remain important, in particular with a view to life style and environmental factors. Such knowledge may further serve as inspiration to the laboratory research, which aims at solving the basic enigmas on a tissue level.

AB - Raviola and Wiesel's monkey eyelid suture studies of the 1970s laid the cornerstone for the experimental myopia science undertaken since then. The aim has been to clarify the basic humoral and neuronal mechanisms behind induced myopization, its eye tissue transmitters in particular. Besides acquiring new and basic knowledge, the practical object of the research is to reduce the burden of human myopia around the world. Acquisition and cost of optical correction is one issue, but associated morbidity counts more, with its global load of myopia-associated visual loss and blindness. The object of the present PubMed literature-based review is to evaluate apparent similarities between experience from disturbed imaging in experimental laboratory science and varieties within the spectrum of childhood human myopia. So far, the main impression is that macroscopical optical deprivation appears absent in the prevalent types of human myopia, nor is myopia a regular sequel where early eye pathology has led to poor imaging and optical deprivation. Optical aberrations of a higher order are a relatively new issue in myopia research, and microstructural deprivation is only marginally dealt within the survey. Links between experimental and human myopia appear mainly occasional, and with only few examples in humans where factual parallels appear credible. Clinical and epidemiological data on refraction remain important, in particular with a view to life style and environmental factors. Such knowledge may further serve as inspiration to the laboratory research, which aims at solving the basic enigmas on a tissue level.

KW - Animals

KW - Cataract

KW - Corneal Diseases

KW - Disease Models, Animal

KW - Humans

KW - Myopia

KW - Sensory Deprivation

U2 - 10.1111/aos.12412

DO - 10.1111/aos.12412

M3 - Review

C2 - 24767542

VL - 92

SP - 724

EP - 729

JO - Acta Ophthalmologica

JF - Acta Ophthalmologica

SN - 1755-375X

IS - 8

ER -

ID: 138426438