Forskning ved Københavns Universitet - Københavns Universitet

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Increased in vitro tetraploidy and mandibular osteomas in patients with and without colorectal diseases.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskning

  • L B Svendsen
  • J O Søndergaard
  • Steffen Bülow
  • K B Lauritsen
  • N V Holm
  • B S Danes
One hundred and seventy-six individuals with various colorectal diseases were investigated simultaneously for increased in vitro tetraploidy in dermal fibroblast cultures and for occult mandibular osteomas. In only 10 of the 176 persons were both presumed markers of colorectal genetic predisposition present in the same individual. No evidence was found that these traits are causally associated. A combination of the two presumed markers showed a tendency towards occurrence in individuals with a positive family history of colorectal cancer among first-degree relatives.
OriginalsprogEngelsk
TidsskriftScandinavian Journal of Gastroenterology
Vol/bind23
Udgave nummer5
Sider (fra-til)529-533
Antal sider5
ISSN0036-5521
StatusUdgivet - 1988

ID: 34109091