Forskning ved Københavns Universitet - Københavns Universitet

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Integrin signaling to the actin cytoskeleton

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

Integrin engagement stimulates the activity of numerous signaling molecules, including the Rho family of GTPases, tyrosine phosphatases, cAMP-dependent protein kinase and protein kinase C, and stimulates production of PtdIns(4,5)P2. Integrins promote actin assembly via the recruitment of molecules that directly activate the actin polymerization machinery or physically link it to sites of cell adhesion.

OriginalsprogEngelsk
TidsskriftCurrent Opinion in Cell Biology
Vol/bind15
Udgave nummer5
Sider (fra-til)572-82
Antal sider11
ISSN0955-0674
StatusUdgivet - okt. 2003
Eksternt udgivetJa

ID: 199433219