Forskning ved Københavns Universitet - Københavns Universitet

Forside

Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • S A Ballard
  • M Williamson
  • B Adler
  • T Vinh
  • S Faine
A primary culture system for the cells of mouse renal-tubular epithelium was established and used to observe the adhesion of leptospires. Virulent strains of serovars copenhageni and ballum attached themselves to epithelial cells within 3 h of infection whereas an avirulent variant of serovar copenhageni did not adhere to epithelial cells at all within the experimental period of 24 h. The saprophytic Leptospira biflexa serovar patoc became attached non-specifically to inert glass surfaces as well as to the cells. The adhesion of leptospires to epithelial cells was not inhibited by homologous antibody.
Udgivelsesdato: 1986-Feb
OriginalsprogEngelsk
TidsskriftJournal of Medical Microbiology
Vol/bind21
Udgave nummer1
Sider (fra-til)59-67
Antal sider8
ISSN0022-2615
StatusUdgivet - 1986

ID: 3046356