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Interference microscopy under double-wavelet analysis: a new approach to studying cell dynamics

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Sosnovtseva, Olga
  • A N Pavlov
  • Nadezda Brazhe
  • Alexey Brazhe
  • L A Erokhova
  • G V Maksimov
  • Erik Mosekilde
This Letter combines a novel experimental approach to the study of intracellular processes with a newly developed technique for multimode time-series analysis. Experiments are performed on isolated pond snail (Lymnaea stagnalis) neurons. Local variations in the cellular refractive index as detected by laser interference microscopy are related to the processes in the cell. A wavelet analysis shows the presence of several identifiable modes in the membrane and intracellular dynamics, and a double-wavelet analysis reveals nonlinear interactions between the regulatory processes in the form of mutual frequency and amplitude modulations.
OriginalsprogEngelsk
TidsskriftPhysical Review Letters
Vol/bind94
Udgave nummer21
Sider (fra-til)218103
ISSN0031-9007
StatusUdgivet - 3 jun. 2005

ID: 33812721