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Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient. / Larsen, P B; Hansen, E G; Jacobsen, L S; Wiis, J; Holst, P; Rottensten, Henrik Hovgaard F; Siddiqui, R; Wittrup, H; Sørensen, A M; Persson, John Stouby; Engbaek, J.

I: European Journal of Anaesthesiology, Bind 22, Nr. 10, 01.10.2005, s. 748-53.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Larsen, PB, Hansen, EG, Jacobsen, LS, Wiis, J, Holst, P, Rottensten, HHF, Siddiqui, R, Wittrup, H, Sørensen, AM, Persson, JS & Engbaek, J 2005, 'Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient', European Journal of Anaesthesiology, bind 22, nr. 10, s. 748-53.

APA

Larsen, P. B., Hansen, E. G., Jacobsen, L. S., Wiis, J., Holst, P., Rottensten, H. H. F., ... Engbaek, J. (2005). Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient. European Journal of Anaesthesiology, 22(10), 748-53.

Vancouver

Larsen PB, Hansen EG, Jacobsen LS, Wiis J, Holst P, Rottensten HHF o.a. Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient. European Journal of Anaesthesiology. 2005 okt 1;22(10):748-53.

Author

Larsen, P B ; Hansen, E G ; Jacobsen, L S ; Wiis, J ; Holst, P ; Rottensten, Henrik Hovgaard F ; Siddiqui, R ; Wittrup, H ; Sørensen, A M ; Persson, John Stouby ; Engbaek, J. / Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient. I: European Journal of Anaesthesiology. 2005 ; Bind 22, Nr. 10. s. 748-53.

Bibtex

@article{a46861003c324c9b95a50f7680c507e2,
title = "Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient",
abstract = "Background and objective: Previous studies mainly conducted on elective patients recommend doses of 0.9-1.2 mg kg[-1] rocuronium to obtain comparable intubation conditions with succinylcholine 1.0 mg kg[-1] after 60 s during a rapid-sequence induction. We decided to compare the overall intubating conditions of standard doses of rocuronium 0.6 mg kg[-1] and succinylcholine 1.0 mg kg[-1] during a strict rapid-sequence induction regimen including propofol and alfentanil. Methods: Male and female patients (ASA I-III) older than 17 yr scheduled for emergency abdominal or gynaecological surgery and with increased risk of pulmonary aspiration of gastric content were randomized to a rapid-sequence induction with succinylcholine 1.0 mg kg[-1] or rocuronium 0.6 mg kg[-1]. Patients with a predicted difficult airway were excluded. A senior anaesthesiologist 'blinded' for the randomization performed the intubation 60 s after injection of the neuromuscular blocker. Intubating conditions were evaluated according to an established guideline. Tracheal intubation not completed within 30 s was recorded as failed. Results: 222 patients were randomized. Three patients had their operation cancelled and 10 did not fulfil the inclusion criteria. Clinically acceptable intubation conditions were present in 93.5{\%} and 96.1{\%} of patients in the succinylcholine group (n=107) and the rocuronium group (n=102), respectively (P=0.59). Conclusions: During a rapid-sequence induction with alfentanil and propofol, both rocuronium 0.6 mg kg[-1] and succinylcholine 1.0 mg kg[-1] provide clinically acceptable intubation conditions in 60 s in patients scheduled for emergency surgery. Under the conditions of this rapid-sequence induction regimen rocuronium may be a substitute for succinylcholine.",
author = "Larsen, {P B} and Hansen, {E G} and Jacobsen, {L S} and J Wiis and P Holst and Rottensten, {Henrik Hovgaard F} and R Siddiqui and H Wittrup and S{\o}rensen, {A M} and Persson, {John Stouby} and J Engbaek",
year = "2005",
month = "10",
day = "1",
language = "English",
volume = "22",
pages = "748--53",
journal = "European Journal of Anaesthesiology",
issn = "0265-0215",
publisher = "Lippincott Williams & Wilkins, Ltd.",
number = "10",

}

RIS

TY - JOUR

T1 - Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient

AU - Larsen, P B

AU - Hansen, E G

AU - Jacobsen, L S

AU - Wiis, J

AU - Holst, P

AU - Rottensten, Henrik Hovgaard F

AU - Siddiqui, R

AU - Wittrup, H

AU - Sørensen, A M

AU - Persson, John Stouby

AU - Engbaek, J

PY - 2005/10/1

Y1 - 2005/10/1

N2 - Background and objective: Previous studies mainly conducted on elective patients recommend doses of 0.9-1.2 mg kg[-1] rocuronium to obtain comparable intubation conditions with succinylcholine 1.0 mg kg[-1] after 60 s during a rapid-sequence induction. We decided to compare the overall intubating conditions of standard doses of rocuronium 0.6 mg kg[-1] and succinylcholine 1.0 mg kg[-1] during a strict rapid-sequence induction regimen including propofol and alfentanil. Methods: Male and female patients (ASA I-III) older than 17 yr scheduled for emergency abdominal or gynaecological surgery and with increased risk of pulmonary aspiration of gastric content were randomized to a rapid-sequence induction with succinylcholine 1.0 mg kg[-1] or rocuronium 0.6 mg kg[-1]. Patients with a predicted difficult airway were excluded. A senior anaesthesiologist 'blinded' for the randomization performed the intubation 60 s after injection of the neuromuscular blocker. Intubating conditions were evaluated according to an established guideline. Tracheal intubation not completed within 30 s was recorded as failed. Results: 222 patients were randomized. Three patients had their operation cancelled and 10 did not fulfil the inclusion criteria. Clinically acceptable intubation conditions were present in 93.5% and 96.1% of patients in the succinylcholine group (n=107) and the rocuronium group (n=102), respectively (P=0.59). Conclusions: During a rapid-sequence induction with alfentanil and propofol, both rocuronium 0.6 mg kg[-1] and succinylcholine 1.0 mg kg[-1] provide clinically acceptable intubation conditions in 60 s in patients scheduled for emergency surgery. Under the conditions of this rapid-sequence induction regimen rocuronium may be a substitute for succinylcholine.

AB - Background and objective: Previous studies mainly conducted on elective patients recommend doses of 0.9-1.2 mg kg[-1] rocuronium to obtain comparable intubation conditions with succinylcholine 1.0 mg kg[-1] after 60 s during a rapid-sequence induction. We decided to compare the overall intubating conditions of standard doses of rocuronium 0.6 mg kg[-1] and succinylcholine 1.0 mg kg[-1] during a strict rapid-sequence induction regimen including propofol and alfentanil. Methods: Male and female patients (ASA I-III) older than 17 yr scheduled for emergency abdominal or gynaecological surgery and with increased risk of pulmonary aspiration of gastric content were randomized to a rapid-sequence induction with succinylcholine 1.0 mg kg[-1] or rocuronium 0.6 mg kg[-1]. Patients with a predicted difficult airway were excluded. A senior anaesthesiologist 'blinded' for the randomization performed the intubation 60 s after injection of the neuromuscular blocker. Intubating conditions were evaluated according to an established guideline. Tracheal intubation not completed within 30 s was recorded as failed. Results: 222 patients were randomized. Three patients had their operation cancelled and 10 did not fulfil the inclusion criteria. Clinically acceptable intubation conditions were present in 93.5% and 96.1% of patients in the succinylcholine group (n=107) and the rocuronium group (n=102), respectively (P=0.59). Conclusions: During a rapid-sequence induction with alfentanil and propofol, both rocuronium 0.6 mg kg[-1] and succinylcholine 1.0 mg kg[-1] provide clinically acceptable intubation conditions in 60 s in patients scheduled for emergency surgery. Under the conditions of this rapid-sequence induction regimen rocuronium may be a substitute for succinylcholine.

M3 - Journal article

VL - 22

SP - 748

EP - 753

JO - European Journal of Anaesthesiology

JF - European Journal of Anaesthesiology

SN - 0265-0215

IS - 10

ER -

ID: 40197484