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Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • A Johansen
  • E-M D Nielsen
  • G Andersen
  • Y H Hamid
  • D P Jensen
  • C Glümer
  • Drivsholm, Thomas
  • K Borch-Johnsen
  • T Jørgensen
  • T Hansen
  • O Pedersen
Polymorphisms of the butyrylcholinesterase gene (BCHE) are reported to associate with Alzheimer's disease and a recent study found a significant association of the BCHE K variant (G1615A/Ala539Thr) with Type 2 diabetes. The objectives of our study were to examine whether the BCHE K variant is associated with Type 2 diabetes or estimates of pancreatic beta cell function in large-scale populations of glucose-tolerant Caucasians.
OriginalsprogEngelsk
TidsskriftDiabetologia
Vol/bind47
Udgave nummer8
Sider (fra-til)1437-41
Antal sider5
ISSN0012-186X
DOI
StatusUdgivet - 1 aug. 2004

ID: 33030584