Forskning ved Københavns Universitet - Københavns Universitet

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Locomotor circuits in the mammalian spinal cord

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskningfagfællebedømt

Intrinsic spinal networks, known as central pattern generators (CPGs), control the timing and pattern of the muscle activity underlying locomotion in mammals. This review discusses new advances in understanding the mammalian CPGs with a focus on experiments that address the overall network structure as well as the identification of CPG neurons. I address the identification of excitatory CPG neurons and their role in rhythm generation, the organization of flexor-extensor networks, and the diverse role of commissural interneurons in coordinating left-right movements. Molecular and genetic approaches that have the potential to elucidate the function of populations of CPG interneurons are also discussed.

OriginalsprogEngelsk
TitelAnnual Review of Neuroscience
Antal sider28
Publikationsdato5 okt. 2006
Sider279-306
ISBN (Trykt)0824324293, 9780824324292
DOI
StatusUdgivet - 5 okt. 2006
NavnAnnual Review of Neuroscience
Vol/bind29
ISSN0147-006X

ID: 194978433