Forskning ved Københavns Universitet - Københavns Universitet


Measuring quality of life in first-episode psychosis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • I Melle
  • Svein Friis
  • U Haahr
  • Jan Olav Johannesen
  • Tor Ketil Larsen
  • S Opjordsmoen
  • J I Roessberg
  • B R Rund
  • Simonsen, Erik
  • P Vaglum
  • T McGlashan

Quality of life (QoL) measures are increasingly recognized as necessary parts of outcome assessments in psychosis. The present paper is a comprehensive study of patients with first-episode psychosis where QoL is measured by the commonly used Lehman Quality of Life Interview (L-QoLI). The aim is to examine if the L-QoLI maintain its original structure when used in a group of patients with first-episode psychosis, and to investigate what determines global subjective QoL with a specific emphasis on premorbid adjustment, duration of untreated psychosis (DUP) and clinical symptoms. The study indicates that the psychometric properties of the L-QoLI do not change significantly when used in first-episode samples. The patients report subjective and objective QoL in the fair to good range, with only a moderate association between the objective and subjective measures. Poor global satisfaction is predicted by being single, abusing drugs, being depressed, having a diagnosis of psychotic affective disorder, having poor premorbid social adjustment and DUP over 10 weeks. The study supports the notion that patients with first-episode psychosis construct QoL in the same way as other groups, and that longer durations of compromised function at this stage produces poor satisfaction with life rather than a downward readjustment of expectations.

TidsskriftEuropean Psychiatry
Udgave nummer7
Sider (fra-til)474-83
Antal sider10
StatusUdgivet - nov. 2005

ID: 186482710