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Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome - Commensalism and Postbiotic Effects

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Standard

Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome - Commensalism and Postbiotic Effects. / Jakobsen, Louise M. A.; Maldonado-Gómez, Maria X.; Sundekilde, Ulrik K.; Andersen, Henrik J.; Nielsen, Dennis S.; Bertram, Hanne C.

I: Metabolites, Bind 10, Nr. 4, 167, 2020.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Jakobsen, LMA, Maldonado-Gómez, MX, Sundekilde, UK, Andersen, HJ, Nielsen, DS & Bertram, HC 2020, 'Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome - Commensalism and Postbiotic Effects', Metabolites, bind 10, nr. 4, 167. https://doi.org/10.3390/metabo10040167

APA

Jakobsen, L. M. A., Maldonado-Gómez, M. X., Sundekilde, U. K., Andersen, H. J., Nielsen, D. S., & Bertram, H. C. (2020). Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome - Commensalism and Postbiotic Effects. Metabolites, 10(4), [167]. https://doi.org/10.3390/metabo10040167

Vancouver

Jakobsen LMA, Maldonado-Gómez MX, Sundekilde UK, Andersen HJ, Nielsen DS, Bertram HC. Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome - Commensalism and Postbiotic Effects. Metabolites. 2020;10(4). 167. https://doi.org/10.3390/metabo10040167

Author

Jakobsen, Louise M. A. ; Maldonado-Gómez, Maria X. ; Sundekilde, Ulrik K. ; Andersen, Henrik J. ; Nielsen, Dennis S. ; Bertram, Hanne C. / Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome - Commensalism and Postbiotic Effects. I: Metabolites. 2020 ; Bind 10, Nr. 4.

Bibtex

@article{29c03080983d456e9d874dbb2a6cb649,
title = "Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome - Commensalism and Postbiotic Effects",
abstract = "Oligosaccharides from human or bovine milk selectively stimulate growth or metabolism of bacteria associated with the lower gastrointestinal tract of infants. Results from complex infant-type co-cultures point toward a possible synergistic effect of combining bovine milk oligosaccharides (BMO) and lactose (LAC) on enhancing the metabolism of Bifidobacterium longum subsp. longum and inhibition of Clostridium perfringens. We examine the interaction between B. longum subsp. longum and the commensal Parabacteroides distasonis, by culturing them in mono- and co-culture with different carbohydrates available. To understand the interaction between BMO and lactose on B. longum subsp. longum and test the potential postbiotic effect on C. perfringens growth and/or metabolic activity, we inoculated C. perfringens into fresh media and compared the metabolic changes to C. perfringens in cell-free supernatant from B. longum subsp. longum fermented media. In co-culture, B. longum subsp. longum benefits from P. distasonis (commensalism), especially in a lactose-rich environment. Furthermore, B. longum subsp. longum fermentation of BMO + LAC impaired C. perfringens’ ability to utilize BMO as a carbon source (potential postbiotic effect).",
keywords = "0000-0002-0544-7464, Co-culture, Gut microbiota, Infant nutrition, Metabolic activity, Microbial interaction",
author = "Jakobsen, {Louise M. A.} and Maldonado-G{\'o}mez, {Maria X.} and Sundekilde, {Ulrik K.} and Andersen, {Henrik J.} and Nielsen, {Dennis S.} and Bertram, {Hanne C.}",
year = "2020",
doi = "10.3390/metabo10040167",
language = "English",
volume = "10",
journal = "Metabolites",
issn = "2218-1989",
publisher = "M D P I AG",
number = "4",

}

RIS

TY - JOUR

T1 - Metabolic Effects of Bovine Milk Oligosaccharides on Selected Commensals of the Infant Microbiome - Commensalism and Postbiotic Effects

AU - Jakobsen, Louise M. A.

AU - Maldonado-Gómez, Maria X.

AU - Sundekilde, Ulrik K.

AU - Andersen, Henrik J.

AU - Nielsen, Dennis S.

AU - Bertram, Hanne C.

PY - 2020

Y1 - 2020

N2 - Oligosaccharides from human or bovine milk selectively stimulate growth or metabolism of bacteria associated with the lower gastrointestinal tract of infants. Results from complex infant-type co-cultures point toward a possible synergistic effect of combining bovine milk oligosaccharides (BMO) and lactose (LAC) on enhancing the metabolism of Bifidobacterium longum subsp. longum and inhibition of Clostridium perfringens. We examine the interaction between B. longum subsp. longum and the commensal Parabacteroides distasonis, by culturing them in mono- and co-culture with different carbohydrates available. To understand the interaction between BMO and lactose on B. longum subsp. longum and test the potential postbiotic effect on C. perfringens growth and/or metabolic activity, we inoculated C. perfringens into fresh media and compared the metabolic changes to C. perfringens in cell-free supernatant from B. longum subsp. longum fermented media. In co-culture, B. longum subsp. longum benefits from P. distasonis (commensalism), especially in a lactose-rich environment. Furthermore, B. longum subsp. longum fermentation of BMO + LAC impaired C. perfringens’ ability to utilize BMO as a carbon source (potential postbiotic effect).

AB - Oligosaccharides from human or bovine milk selectively stimulate growth or metabolism of bacteria associated with the lower gastrointestinal tract of infants. Results from complex infant-type co-cultures point toward a possible synergistic effect of combining bovine milk oligosaccharides (BMO) and lactose (LAC) on enhancing the metabolism of Bifidobacterium longum subsp. longum and inhibition of Clostridium perfringens. We examine the interaction between B. longum subsp. longum and the commensal Parabacteroides distasonis, by culturing them in mono- and co-culture with different carbohydrates available. To understand the interaction between BMO and lactose on B. longum subsp. longum and test the potential postbiotic effect on C. perfringens growth and/or metabolic activity, we inoculated C. perfringens into fresh media and compared the metabolic changes to C. perfringens in cell-free supernatant from B. longum subsp. longum fermented media. In co-culture, B. longum subsp. longum benefits from P. distasonis (commensalism), especially in a lactose-rich environment. Furthermore, B. longum subsp. longum fermentation of BMO + LAC impaired C. perfringens’ ability to utilize BMO as a carbon source (potential postbiotic effect).

KW - 0000-0002-0544-7464

KW - Co-culture

KW - Gut microbiota

KW - Infant nutrition

KW - Metabolic activity

KW - Microbial interaction

U2 - 10.3390/metabo10040167

DO - 10.3390/metabo10040167

M3 - Journal article

C2 - 32344519

AN - SCOPUS:85084459584

VL - 10

JO - Metabolites

JF - Metabolites

SN - 2218-1989

IS - 4

M1 - 167

ER -

ID: 242656750