Forskning ved Københavns Universitet - Københavns Universitet


Microtermolides A and B from termite-associated Streptomyces sp. and structural revision of vinylamycin

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Gavin Carr
  • Poulsen, Michael
  • Jonathan L. Klassen
  • Yanpeng Hou
  • Thomas P. Wyche
  • Tim S. Bugni
  • Cameron R. Currie
  • Jon Clardy
Microtermolides A (1) and B (2) were isolated from a Streptomyces sp. strain associated with fungus-growing termites. The structures of 1 and 2 were determined by 1D- and 2D-NMR spectroscopy and high-resolution mass spectrometry. Structural elucidation of 1 led to the re-examination of the structure originally proposed for vinylamycin (3). Based on a comparison of predicted and experimental (1)H and (13)C NMR chemical shifts, we propose that vinylamycin's structure be revised from 3 to 4.
TidsskriftOrganic Letters
Udgave nummer11
Sider (fra-til)2822–2825
Antal sider4
StatusUdgivet - 2012

ID: 38166744