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Molluscicidal saponins from Phytolacca dodecandra

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Two new monodesmosidic saponins were isolated from an aqueous extract of the Ethiopian strain 44 of Phytolacca dodecandra. Their structures were established as 3-0-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-galactopyranosyl-(1-->3)] -beta-D-glucopyranosyloleanolic acid and 3-O-beta-D-xylopyranosyl-(1-->6)-O-beta-D-gluco-pyranosyl-(1-->3)]-beta -D-glucopyranosyloleanolic acid mainly by spectroscopic methods (LSIMS, H-1 NMR, COSY, NOESY, TOCSY, J-resolved H-1 NMR, C-13 NMR, HETCOR). The saponins are potent molluscicides against the schistosomiasis transmitting snail Biomphalaria glabrata with LC50 values of 2 and 5 ppm, respectively.
OriginalsprogUdefineret/Ukendt
TidsskriftPhytochemistry
Vol/bind32
Udgave nummer5
Sider (fra-til)1167-1171
Antal sider5
ISSN0031-9422
StatusUdgivet - 1993

    Forskningsområder

  • phytolacca-dodecandra phytolaccaceae endod strain 44 endod-s molluscicides triterpenoid saponins oleanolic acid lherit

ID: 38062288